Pregnant, Lactating Women Underrepresented in IBD Clinical Trials
Investigators assessed disparities in IBD clinical trials regarding a lack of inclusion of pregnant, lactating women; older adults; and racial and ethnic minorities.
Ulcerative Colitis
Ulcerative colitis
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Non-Anti-TNF-a Antibody Therapies Effective as Second-Line Treatment for UC
Investigators examined whether a patient’s initial response to anti-tumor necrosis factor (TNF)-a antibody could inform subsequent treatment in ulcerative colitis.
What Factors Help Predict Postoperative Fentanyl Use in Patients With IBD?
Researchers sought to identify factors that could help predict postoperative opioid consumption in patients with IBD.
Early Anti-TNF Therapy Helps Reduce Health Care Utilization in CD
Researchers compared the difference in overall health care utilization in patients with IBD who started anti-TNF therapy 2 years vs more than 2 years postdiagnosis.
Histologic Remission With NHI Effective for Predicting Relapse-Free Survival in UC
A team of researchers assessed histologic activity in patients with ulcerative colitis who were in endoscopic and clinical remission, using the NHI score to predict future relapse.
How Prevalent Is Polypharmacy Among Patients With Inflammatory Bowel Disease?
Researchers sought to determine the prevalence of polypharmacy in adults with Crohn disease and ulcerative colitis, collectively referred to as IBD.
Does Higher Adalimumab Induction and Maintenance Dosing Lead to Remission in UC?
Researchers examined the efficacy of higher adalimumab induction and maintenance dose regimens in adults with ulcerative colitis.
A Machine-Learning-Based Predictor for Histological Remission in Ulcerative Colitis
Researchers sought to create a histological index that would help evaluate inflammation and predict clinical outcomes in patients with ulcerative colitis.
C-Reactive Protein: An Alternative Diagnostic Criterion to ESR for Severe UC
Researchers sought to identify the equivalent C-reactive protein cutoff for an erythrocyte sedimentation rate greater than 30 mm/h in severe UC.
Model Predicts CRC Risk in UC Patients With LGD
For patients with ulcerative colitis, large, unresected, multifocal low-grade dysplasia and recent moderate/severe histological inflammation are associated with elevated risk of developing advanced neoplasia.
Ambulatory Care May Be Effective and Feasible in Patients With ASUC
Investigators compared the safety and efficacy of different ambulatory care pathways vs traditional inpatient care in patients with acute severe ulcerative colitis.
Anemia, Need for Corticosteroids May Predict Complicated Disease Course in UC
Researchers assessed clinical predictors for a complicated disease course in patients recently diagnosed with ulcerative colitis.
CAR Associated With Endoscopic Activity in UC
Researchers assessed the association between CRP-to-albumin ratio and ulcerative colitis regarding clinical remission, mucosal healing, and endoscopic disease severity.
FDA to Review Abrilada for Interchangeability With Humira
The PAS is supported by data from the REFLECTIONS B538-12 study, which assessed multiple switches between Abrilada and Humira, in addition to methotrexate, in adults with moderate to severe rheumatoid arthritis.
Increasing Global Incidence and Prevalence of Pediatric IBD
Investigators assessed geographic and longitudinal trends in the incidence and prevalence of pediatric-onset inflammatory bowel disease.
Early Change in FC Levels Predicts Remission Among Children With UC
Investigators assessed whether changes in fecal calprotectin levels better predict achievement of remission than levels at diagnosis in children with ulcerative colitis.
CRP Can Help Assess Severity of Acute Ulcerative Colitis
A C-reactive protein cutoff is a sensitive and practical alternative to erythrocyte sedimentation rate as a criterion to help determine ulcerative colitis activity.
BMD Positively Associated With Physical Activity Among Children With IBD
Investigators assessed the relationship between physical activity, body mass index, and body composition among pediatric patients with inflammatory bowel disease.
Comparison of Biological Therapies and Small Molecules for Moderate to Severe UC
Investigators ranked the efficacy and safety of biological and small molecule treatments for moderate to severe ulcerative colitis.
Psychosocial Wellbeing: The Unmet Needs of Patients With IBD
Investigators highlight the burdens caused by unaddressed or uncontrolled symptoms of IBD and suggest ways physicians could address these burdens in clinical practice.
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