Humira Approved for Pediatric Ulcerative Colitis
The pediatric approval was based on data from the multicenter, randomized, double-blind phase 3 ENVISION I study.
Ulcerative Colitis
Ulcerative colitis
Latest News
Assessment of Acute Severe Ulcerative Colitis During the COVID-19 Pandemic
The PROTECT-ASUC Study Group conducted a multicenter, observational, case-control study to assess the impact of the COVID-19 pandemic on the management of acute severe ulcerative colitis.
Influence of PPI Therapy on Outcome of Infliximab Therapy in IBD
A team of investigators sought to determine how concomitant proton pump inhibitor treatment influences response to infliximab therapy in patients with inflammatory bowel disease.
Kidney Function Monitoring Strategy to Prevent 5-ASA Nephrotoxicity in IBD
Investigators performed a literature review of current strategies for monitoring kidney function in patients undergoing treatment with 5-ASA for inflammatory bowel disease.
Ozanimod Gets Priority Review for Ulcerative Colitis
The submission is supported by data from the True North trial that assessed ozanimod as an induction and maintenance therapy for adults with moderately to severely active UC who had an inadequate response to prior treatment.
Study Finds Link Between Depression, Anxiety Symptoms and Disease Activity in IBD
A team of investigators examined the association between disease activity in individuals with inflammatory bowel disease and the development of symptoms of depression and anxiety.
PICaSSO: A Useful Score to Assess Healing in UC
Researchers investigated the correlation of PICaSSO and other established endoscopic scores against multiple histologic indices and prospectively assessed outcomes.
Clinical Tool Helps Optimize Vedolizumab Treatment in Patients With UC
An international team of investigators created a clinical decision support tool to assist in identifying patients with ulcerative colitis most likely to benefit from treatment with vedolizumab.
De-Escalate or Discontinue Biologics in IBD?
Although the definition of remission varies, the goal of IBD treatment is to achieve and sustain remission.
Bacterial and Fungal Profiles Estimate Infliximab Response in IBD
A team of investigators sought to determine the influence of infliximab on gut bacterial and fungal composition in patients with inflammatory bowel disease.
Increased Fecal Proteolytic Activity May Be Potential UC Biomarker
A team of investigators studied a group of asymptomatic patients who were at increased risk of developing inflammatory bowel disease to assess proteolytic activity in advance of a diagnosis of ulcerative colitis.
Improved Psychological Support Needed After Stoma Surgery
Interview study identified categories in which improved psychological support services are needed for these patients.
Socioeconomic Status Influences IBD Outcomes
Lower socioeconomic status is associated with worse outcomes for inflammatory bowel disease.
Expanded Insight Guides Therapeutic Strategy in IBD Amid COVID-19
Although the emergence of COVID-19 initially called the continuation of inflammatory bowel disease (IBD) therapy into question, treatment has proceeded — albeit with added considerations.
Treatment for ASUC in Pregnant Women Is Safe and Effective
Investigators studied the outcomes of pregnant women hospitalized with acute severe ulcerative colitis.
Extended Tofacitinib Induction Therapy Safely Elicits Responses in UC
Investigators tested the safety and efficacy of an additional 8-week course of tofacitinib monotherapy in patients with ulcerative colitis to determine whether a longer course of induction therapy would induce clinical responses.
Marked Decline in 5-Year Surgery Rates Seen for UC, CD
Investigators analyzed the surgical risk for ulcerative colitis and Crohn disease in contemporary, population-based inception cohorts vs 20th century cohorts.
Acupuncture May Be Effective for UC, But Further Study Needed
Investigators conducted a systemic review and meta-analysis to assess acupuncture’s efficacy with or without conventional ulcerative colitis therapy.
Computer Algorithm May Offer Automated Means of Histologic Scoring in UC
Investigators evaluated the efficacy of a computer-aided algorithm in assessing histologic remission in ulcerative colitis.
Biologics May Reduce Surgery Rates in CD, UC
The investigators used a commercial database containing electronic health record data from 26 major United States healthcare systems to assess the effect of biologics on surgery rates in the IBD setting.
-
Loading...
-
Loading...
Want to read more?
Please login or register first to view this content.
