Genetic Liability to Cigarette Smoking Associated With a Wide Range of Diseases
Cigarette smoking has a causal role in a spectrum of diseases, but has been linked with decreased risk of prostate cancer and Parkinson’s disease.
Cigarette smoking has a causal role in a spectrum of diseases, but has been linked with decreased risk of prostate cancer and Parkinson’s disease.
The phase 3 EoE KIDS study included 102 children with active eosinophilic esophagitis based on histologic improvement meeting validated histologic criteria.
Researchers sought to determine if receiving combined treatment with a PPI and a food elimination diet could help patients with eosinophilic esophagitis achieve remission.
Survival is similar with early versus delayed surgery in stage I esophageal cancer, while for stage II/III cancer, five-year survival is improved with early surgery.
The U.S. FDA approved the monoclonal antibody Dupixent (dupilumab) to treat eosinophilic esophagitis patients 12 years and older.
Researchers investigated the relationship between eosinophilic esophagitis at the time of diagnosis and disease severity, and the change in disease before and after treatment.
While food allergies may affect response to the medication, environmental allergies do not, the report says.
Researchers examined the prevalence of Barrett esophagus and esophageal cancer according to young, middle-aged, and older adult age groups.
To survey patients after successful treatment, researchers developed a prediction model for recurrent dysplasia after eradication of Barrett esophagus.
The authors recommend that dysplasia of any grade detected on BE biopsies be confirmed by a second pathologist who has expertise in gastrointestinal pathology.