Exploring the Impact of Nutrition on the Gut Microbiome
The systemic effects of the gut microbiome persist throughout the life course, though neonatal and early-life disruptions may have the greatest consequences on gut health.
Pediatric Gastroenterology
PEDIATRIC GASTROENTEROLOGY
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Budesonide Oral Suspension Improves Multiple Outcomes in Pediatric Eosinophilic Esophagitis
Budesonide oral suspension improved histologic, endoscopic, and both histologic and symptomatic outcomes in children with eosinophilic esophagitis compared with placebo.
Humira Approved for Pediatric Ulcerative Colitis
The pediatric approval was based on data from the multicenter, randomized, double-blind phase 3 ENVISION I study.
Medical Scribe Program Improves Productivity at Pediatric Clinic
Researchers assessed the impact of medical scribes on operations in a pediatric clinic, including the effect on clinician productivity and workflow efficiency.
Total Bilirubin Important Risk Factor for Pediatric Bile Duct Stones
A team of investigators evaluated the performance of adult-based criteria for predicting common bile duct stones in children.
Type 1 Diabetes With Celiac Disease Increases Depression Risk in Adolescents
Celiac disease is known to be associated with depression and anxiety in adults with type 1 diabetes and celiac disease. In this study, researchers examine the theory in adolescents with T1D and celiac disease.
Child Proton Pump Inhibitor Use May Increase Asthma Risk
Initiation of proton pump inhibitor (PPI) use is associated with an increased risk for asthma among children.
Triple Therapy for Helicobacter pylori Eradication Safe for Adolescents
A team of investigators conducted a prospective, multicenter study to assess the safety of H pylori eradication therapy in adolescent students.
Infants With COVID-19 May Present With GI Symptoms
Among 10 infants hospitalized with COVID-19, most had mild disease and most commonly presented with gastrointestinal symptoms.
Novel Therapy Fast Tracked for GI Dysfunction in Peds Undergoing Heart Surgery
The designation is based on positive topline data from a phase 2 study of 120 adults following open-heart surgery.
Neighborhood Deprivation Predicts Poorer Liver Transplant Outcomes in Children
A team of researchers sought to determine whether neighborhood deprivation affected outcomes in pediatric patients having undergone hepatic transplantation.
Validation of Fatty Liver Scoring Systems for the Diagnosis of NAFLD in Adolescents
A team of investigators sought to identify the accuracy of diagnostic tools for the detection of nonalcoholic fatty liver disease in adolescent patients.
Gluten-Free Diet Induces Changes in Intestinal Microbiota of Children With Celiac Disease
Investigators characterized the gut microbiota of children with celiac disease to collect data on the determinants of the microbiota likely to change in children following a gluten-free diet.
Computed Tomography Use Down for ED Evaluation of Abdominal Pain in Children
The researchers found that for children, the use of CT increased from 1.2 percent in 1997, peaked at 16.6 percent in 2010, and declined slightly in 2016.
Probiotic Inhibits Viral Proliferation in Rotaviral Gastroenteritis
Investigators evaluated the safety and efficacy of Lactobacillus plantarum (LRCC5310), a probiotic organism, in children hospitalized with rotaviral gastroenteritis.
Fish Oil Lipid Emulsion Associated With Reduced Liver Injury, Transplantation in Pediatric IFALD
Researchers compared aminotransferase with platelet ratio index, liver transplantation, and mortality rates in children with intestinal failure-associated liver disease who received either fish oil- or soybean oil-based intravenous lipid emulsion therapy.
Functional Constipation and IBS More Common in Pediatric Celiac Disease
Celiac disease in children leads to an increased risk for functional constipation and irritable bowel syndrome compared with healthy controls.
Multiomic Study Investigates Mucosal Healing in Pediatric Crohn Disease
The goal of this study was to describe changes in the microbiota, metabolome, and protease activity related to mucosal healing in established pediatric Crohn disease.
Low-Dose Zinc Therapy Effective for Treating Diarrhea Among Young Children
The goal of this study was to see if a lower dosage of zinc than 20 mg/d could decrease acute diarrhea in young children without increasing vomiting.
Autism Triggers Nonverbal Manifestation of GI Symptoms in Children
Developmental and behavioral functioning often associated with children diagnosed with ASD, such as sensory sensitivity, aggression, and sleep disorders, may be linked to a nonverbal manifestation of gastrointestinal symptoms.
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