Renaming and Redefining Pediatric Nonalcoholic Fatty Liver Disease
An international panel proposed updated criteria for disease diagnosis, along with a more age-appropriate disease name and definition, for pediatric patients with NAFLD.
Pediatric Gastroenterology
PEDIATRIC GASTROENTEROLOGY
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Cognitive-Behavioral Therapy May Reduce Pain Associated With Functional Abdominal Pain Among Children
Investigators compared the efficacy of cognitive-behavioral therapy vs an attention control for reducing abdominal pain in children with functional abdominal pain.
Probiotics May Not Affect Symptom Duration in Pediatric Acute Gastroenteritis
Investigators assessed the efficacy of probiotics based on duration of symptoms and frequency of diarrhea at the time of treatment initiation in pediatric patients with acute gastroenteritis.
Does the Gut Microbiome Hold the Key for Early Identification of Autism Spectrum Disorder?
The investigators sought to determine the down-staging success rate and intention-to-treat outcomes according to uniform criteria in patients with hepatocellular carcinoma.
Children With Intestinal Failure Present With Lower Levels of Physical Activity and Greater Fatigue Than Healthy Children
Researchers compared levels of physical function, activity, and fatigue in children with intestinal failure vs healthy controls.
Pediatric Gastroenterologists Prefer Initial Withdrawal of Immunomodulator in Step-Down Process in PIBD
Researchers assessed the practices favored by pediatric gastroenterologists for combination immunosuppression in patients with pediatric inflammatory bowel disease.
Maternal Psychological Disposition May Be Linked to Functional Gastrointestinal Disorders in Newborns
Investigators assessed the association between functional gastrointestinal disorders in infants and psychological factors in their mothers.
No Differences Noted in Vitamins C and E, Fatty Acid Content in Human Milk According to Infant Sex
Investigators assessed the relationship between infant sex and the concentrations of vitamin C, E, and fatty acids in human milk.
Dientamoeba fragilis Colonization Is Associated With Increased Gut Microbiota Alpha Diversity
Investigators sought to compare the gut microbiota composition of children with and without D fragilis colonization and assess the impact of metronidazole on gut microbiota diversity and composition in D fragilis carriers.
Psychotropic Medications May Significantly Reduce Chronic Pain in Pediatric Patients
Study authors conducted a meta-analysis of randomized controlled trials to study the effectiveness of psychotropic medications in children and adolescents with chronic pain.
Almost Half of Pediatric Opioid Prescriptions Considered High-Risk
Almost half of pediatric opioid prescriptions are considered high-risk by one or more metric, and high-volume prescribers write more than half of the prescriptions.
Patient-Reported Outcomes Informative, Valid Measures of Pediatric UC
Investigators conducted a longitudinal cohort study of patients with UC to evaluate how PROMIS Pediatric measures relate to disease activity and health-related quality of life.
Poorly Developed Emotion Regulation Skills During Early Childhood Linked to Teen Anorexia
The researchers investigated how emotion regulation trajectories in children from 3 to 7 years of age were associated with symptoms of anorexia nervosa and atypical anorexia nervosa in adolescence.
Gastro-Resistant Mixed Micelles Enhance Vitamin K Absorption Under Cholestatic Conditions
Researchers explain current prophylactic regimen failures in ensuring effective vitamin K absorption under cholestatic conditions and demonstrate how gastro-resistant mixed micelles could be used to overcome these limitations.
Experts Discuss the Management of Childhood Obesity
Although the rise in pediatric obesity predates the COVID-19 pandemic, stressors experienced during the pandemic exposed inequities in children’s health.
Safety and Efficacy of Chinese Herbal Medicine for Treating Childhood Constipation
Investigators assessed the safety and efficacy of XiaojiDaozhi Decoction, a form of Chinese herbal medicine, in relieving childhood constipation.
Uncomplicated Appendicitis in Children: To Operate or Not to Operate?
Because outcomes of appendectomy vary by patient age, family income, and transfer status, the researchers compared outcomes in these subgroups.
Epclusa Approved for Younger Patients With Chronic Hepatitis C
The expanded approval was based on data from an open-label phase 2 trial that evaluated Epclusa in 41 patients 3 years to less than 6 years of age with chronic HCV infection.
Hill Grade on EGD Is Associated With GER in Children and Adolescents
Investigators sought to evaluate the relationship between Hill grade confirmed with EGD and the degree of gastroesophageal reflux in children with GERD.
A Systematic Review of Cluster Headache Among the Pediatric Population
The researchers’ goal was to describe the clinical characteristics and therapeutic options available to pediatric patients with cluster headache.
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