Pancreatic Disorders

Jennifer Champagne, PharmD, RPh, BCPS

What Is the Clinical Course for Pediatric Patients With Asparaginase-Associated Pancreatitis?

A team of researchers assessed the clinical characteristics and short-term outcomes of children with asparaginase-associated pancreatitis.

Lower Mortality With Endoscopic Drainage for Necrotizing Pancreatitis

For patients with necrotizing pancreatitis, the rate of fistula formation and mortality is lower with endoscopic drainage (ED) than with other surgical drainage methods.

Increased Pancreatic Enzymes Prevalent in COVID-19 and Tied to Poor Outcomes

Shannon Storms

In this meta-analysis, researchers assessed whether an increase in pancreatic enzymes is associated with an increased risk for severe disease and poor outcomes in patients with COVID-19 infection.

Safety and Efficacy of EUS-Guided Drainage of Pancreatic Fluid Collection Using LAMS

Researchers sought to confirm the good safety and efficacy profile of using LAMS in EUS-guided drainage for pancreatic fluid collection in a real-world setting.

Eligibility Criteria Add to Race Gap in Pancreatic Cancer Clinical Trials

Traditional eligibility criteria differentially exclude Black patients from participating in clinical trials for pancreatic ductal adenocarcinoma.

Hypertension Medications Linked to Lower Mortality After Pancreatic Cancer Diagnosis

Use of angiotensin II receptor blockers and angiotensin I converting enzyme inhibitors after a pancreatic cancer diagnosis is associated with a reduced mortality risk.

Rectal Indometacin Decreases Risk for Postextracorporeal Shock Wave Lithotripsy Pancreatitis

Investigators assessed the use of rectal indometacin for reducing the incidence of postextracorporeal shock wave lithotripsy pancreatitis.

Model Using Routine Clinical Data May Predict Pancreatic Cancer Risk

A model using routine clinical information can predict pancreatic ductal adenocarcinoma (PDA) following diagnosis of impaired fasting glucose.

General Gastroenterology

Alcohol-Related GI and Liver Disease Rates Increase in Women, Black Patients During COVID-19 Pandemic

Investigators assessed the prevalence of alcohol-related gastrointestinal and liver disorders before vs during the COVID-19 pandemic.

Cystic Fibrosis Transmembrane Conductance Regulator Modulators Decrease Hospitalization Rates

Investigators assessed rates of hospitalization for acute pancreatitis among patients with cystic fibrosis (CF) receiving CF transmembrane conductance regulator therapy.

Rectal Indomethacin Ineffective for Preventing Clinical Progression in High-Risk Acute Pancreatitis

Investigators assessed the efficacy of rectal indomethacin at reducing systemic inflammatory response syndrome score and clinical progression in patients with acute pancreatitis.

White pills, money, stethoscope, health care

Drug Funding Reimbursement Associated With Improved Survival in Advanced Pancreatic Cancer

Investigators assessed changes in survival associated with drug funding approvals and treatment with GEMNAB or FOLFIRINOX in patients with advanced pancreatic cancer.

General Gastroenterology

Oral vs IV Antibiotics for Pseudomonas aeruginosa Infection in Patients With Cystic Fibrosis

Estie Mermelstein, MSN, FNP-BC

Researchers conducted a study to compare the effects of intravenous vs oral antibiotics therapy in patients with a pulmonary infection caused by Pseudomonas aeruginosa secondary to cystic fibrosis.

Postponed Catheter Drainage for Infected Necrotizing Pancreatitis Associated With Decreased Rates of Invasive Interventions

Investigators compared immediate vs postponed catheter drainage as part of treatment approach for infected necrotizing pancreatitis and their effects on clinical outcomes.

Acute Pancreatitis Incidence Increases Globally

Investigators assessed the incidence of acute pancreatitis from 1961 onward, as stratified by age, sex, and cause of pancreatitis.

PRECEDE Consortium Develops Strategy for Improving Early Detection of Pancreatic Cancer

Investigators reviewed current pancreatic cancer screening practices and offered recommendations to overcome challenges associated with improving screening efficacy.