Multiple Factors Linked to Hospital Readmission Following Pancreatectomy
Results of this study showed no improvement in the rate of 30-day hospital readmission for patients with cancer undergoing pancreatectomy between 2005 and 2011.
Pancreatic Disorders
PANCREATIC DISORDERS
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Patients With Chronic Pancreatitis at Increased Risk for Diabetes Emergencies
Chronic pancreatitis is associated with increased risk for diabetes-associated emergencies, including diabetic ketoacidosis.
New Pancreaze Formulation Approved With Extended Shelf Life
The Food and Drug Administration has approved a new formulation of Pancreaze (pancrelipase; Vivus) Delayed Release Capsules which would allow for an extended shelf life of 36 months.
Addition of Pegilodecakin to FOLFOX Did Not Improve OS in Metastatic Pancreatic Cancer
Promising results from an earlier-phase study of FOLFOX plus pegilodecakin in metastatic PDAC refractory to gemcitabine provided a rationale for this study.
A Model for Predicting the Risk of Healthy Organ Exposure in Patients With Locally Advanced Pancreatic Cancer Treated With SBRT
Exceeding tolerances of healthy organs-at-risk as a result of daily anatomical deformations is a concern for patients with LAPC treated with SBRT.
Lynparza Gains Pancreatic Cancer Indication
The Food and Drug Administration (FDA) has approved Dayvigo (lemborexant; Eisai) for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance in adult patients.
No Link Found Between Hepatitis C Infection and Extrahepatic Cancers
A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.
Resection Should Be Considered Even in Certain Smaller pNETs
Patients who had tumors measuring 1.5 cm to 2 cm were at double the risk for lymph node metastasis.
Resistance to Immune Checkpoint Inhibition in Pancreatic Cancer
Research presented at SITC 2019 looks at 2 different mechanisms for resistance to immune checkpoint inhibition in pancreatic ductal adenocarcinoma.
Development of Validated Method to Assess, Characterize Pain Mechanisms in Chronic Pancreatitis
Pain phenotypes can be used in the future to attempt prediction of response to treatment in patients with painful chronic pancreatitis and thus provides a framework for personalized pain management.
Effects of Surgeon Volume, Nurse-to-Patient Ratio on Potential Complications With Pancreaticoduodenectomy
Although higher nurse-to-patient ratios ensure good outcomes for patients undergoing pancreaticoduodenectomy, PD-specific surgeon volume has a greater effect on risks of complications for these patients.
Gene Fusions Found in Pancreatic, Biliary IOPNs
Patterns of genetic alterations could guide management.
PERT Led to Insignificant Body Weight Increase in Those With PEI
Pancreatic enzyme replacement therapy (PERT) increased body weight of individuals with pancreatic exocrine insufficiency (PEI) following pancreatoduodenectomy as compared with placebo; however, the effect was not significant.
FCSEMS May Be an Effective First-Line Treatment for Chronic Pancreatitis-Associated BBSs
The study researchers concluded that endoscopic biliary drainage with temporary FCSEMS placement be considered a first-line therapy for CP-associated BBS, and that surgery should still be considered in patients who fail stricture resolution following 1 year indwell.
Childhood Episode of Pancreatitis May Increase Risk for Diabetes Later
A history of a clinically resolved, single event of acute pancreatitis in childhood is associated with an increased risk for diabetes during young adulthood.
Acute Pancreatitis in Childhood May Increase Risk for Type 2 Diabetes
Patients with a history of acute pancreatitis may require closer follow-up and control of diabetes risk factors in young adulthood.
Diverse Risk Factors Associated With Calcifications in Chronic Pancreatitis
Pancreatic calcifications are associated with diverse etiological risk factors in patients with chronic pancreatitis (CP), attesting to the complexity of CP as a disease, and possibly having implications for disease classification.
No Association Between Antihypertensive Drugs and Pancreatic Cancer Risk
The study did not observe any clinically relevant association between use of antihypertensive drugs and pancreatic cancer risk in patients with chronic pancreatitis.
Antithyroid Drugs and Risk for Acute Pancreatitis: Is There a Link?
Based on a case-crossover analysis, there was an increased risk for acute pancreatitis associated with ongoing methimazole/carbimazole or propylthiouracil treatment.
Necrotizing Pancreatitis: Colonic and Pleural Involvement
The study highlights the complexity of patients with necrotizing pancreatitis and the importance of early recognition of possible complications colonic and pleural complications.
Advanced ML Superior to TNM Staging in Predicting Pancreatic Cancer Survival
Traditional prognostic evaluation methods, ie, TNM staging, do not incorporate certain clinical and socioeconomic factors that impact patient survival.
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