Utility of Intracystic Glucose for Diagnosis of Mucinous, Non-Mucinous Pancreatic Cysts Examined
Intracystic glucose concentration outperformed intracystic Carcinoembryonic Antigen as a diagnostic marker for mucinous cysts.
Pancreatic Disorders
PANCREATIC DISORDERS
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Zenocutuzumab Gets Orphan Drug Designation for Pancreatic Cancer
Zenocutuzumab is a first-in-class bispecific antibody that binds to HER2 and HER3 receptors, thereby blocking the interaction of HER3 with its ligand neuregulin 1 (NRG1) or NRG1-fusion proteins.
Study Finds Primary Precut Sphincterotomy Better Than Early Precut for Preventing Post-ERCP Pancreatitis
A randomized controlled trial was performed to assess the safety and efficacy of primary precut sphincterotomy to access the bile duct during endoscopic retrograde cholangiopancreatography.
Underutilization of Indomethacin for Prevention of Pancreatitis Following ERCP
A team of investigators conducted a retrospective study to assess the use of indomethacin as prophylaxis of pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography.
Diagnosing and Managing Patients With Primary Pancreatic Lymphoma
Because primary pancreatic lymphoma is a rare disease, optimal diagnostic and therapeutic protocols have not yet been established.
Distinct Phenotype of Pancreatitis Observed in Patients With SARS-CoV-2 Infection
SARS-CoV-2-associated pancreatitis may represent a distinct phenotype of pancreatitis characterized by metabolic stress, abdominal pain, and specific patterns of inflammation.
Best Practices to Screen for Pancreatic Cancer in High-Risk Individuals
A group of researchers released a review describing indications of pancreatic cancer (PC) in the screening of high risk individuals.
Platinum Therapy May Up Survival in Pancreatic Cancer With DNA Repair Defects
PFS longer in pancreatic ductal adenocarcinoma with versus without homologous recombination deficiency
Update on Potential Risks Associated With Liquid-Filled Intragastric Balloons
Post-approval study results on the risk of hyperinflation, acute pancreatitis, and death associated with the use of liquid-filled intragastric balloons have been made available by the FDA.
Pattern of Mild Pancreatic Injury Present in Patients With COVID-19
Mild pancreatic injury patterns were observed in a group of patients who were diagnosed with COVID-19 pneumonia, according to results published in Gastroenterology.
Early Onset ICP Likely Related to Underlying Genetic Variants
There are significant differences in the clinical features of early, late, and alcohol-related idiopathic chronic pancreatitis.
Lidocaine Reduces Propofol Need During Endoscopic Retrograde Cholangiopancreatography
A team of investigators from China sought to assess the effect of sedation with intravenous lidocaine during endoscopic retrograde cholangiopancreatography (ERCP).
Molecularly Matched Therapy Promising in Pancreatic Cancer
Receipt of molecularly matched therapy is associated with improved outcomes in patients with pancreatic cancer.
Treatment Options for Pancreatic Neuroendocrine Tumors
In the management of PNETs it is important to differentiate between functional and nonfunctional PNETs in order to determine the course of treatment.
Benefits of Insulin Plus Pramlintide in Artificial Pancreas Systems
A novel dual-hormone artificial pancreas system that delivers both rapid insulin and pramlintide was found to improve glucose control.
Natural Genetic Variation in a Calcium Channel Linked to Chronic Pancreatitis
Natural genetic variants in a calcium-selective ion channel gene, TRPV6, appear to influence early-onset chronic pancreatitis.
Multiple Factors Linked to Hospital Readmission Following Pancreatectomy
Results of this study showed no improvement in the rate of 30-day hospital readmission for patients with cancer undergoing pancreatectomy between 2005 and 2011.
Patients With Chronic Pancreatitis at Increased Risk for Diabetes Emergencies
Chronic pancreatitis is associated with increased risk for diabetes-associated emergencies, including diabetic ketoacidosis.
New Pancreaze Formulation Approved With Extended Shelf Life
The Food and Drug Administration has approved a new formulation of Pancreaze (pancrelipase; Vivus) Delayed Release Capsules which would allow for an extended shelf life of 36 months.
Addition of Pegilodecakin to FOLFOX Did Not Improve OS in Metastatic Pancreatic Cancer
Promising results from an earlier-phase study of FOLFOX plus pegilodecakin in metastatic PDAC refractory to gemcitabine provided a rationale for this study.
A Model for Predicting the Risk of Healthy Organ Exposure in Patients With Locally Advanced Pancreatic Cancer Treated With SBRT
Exceeding tolerances of healthy organs-at-risk as a result of daily anatomical deformations is a concern for patients with LAPC treated with SBRT.
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