Best Practices to Screen for Pancreatic Cancer in High-Risk Individuals
A group of researchers released a review describing indications of pancreatic cancer (PC) in the screening of high risk individuals.
Pancreatic Disorders
PANCREATIC DISORDERS
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Platinum Therapy May Up Survival in Pancreatic Cancer With DNA Repair Defects
PFS longer in pancreatic ductal adenocarcinoma with versus without homologous recombination deficiency
Update on Potential Risks Associated With Liquid-Filled Intragastric Balloons
Post-approval study results on the risk of hyperinflation, acute pancreatitis, and death associated with the use of liquid-filled intragastric balloons have been made available by the FDA.
Pattern of Mild Pancreatic Injury Present in Patients With COVID-19
Mild pancreatic injury patterns were observed in a group of patients who were diagnosed with COVID-19 pneumonia, according to results published in Gastroenterology.
Early Onset ICP Likely Related to Underlying Genetic Variants
There are significant differences in the clinical features of early, late, and alcohol-related idiopathic chronic pancreatitis.
Lidocaine Reduces Propofol Need During Endoscopic Retrograde Cholangiopancreatography
A team of investigators from China sought to assess the effect of sedation with intravenous lidocaine during endoscopic retrograde cholangiopancreatography (ERCP).
Molecularly Matched Therapy Promising in Pancreatic Cancer
Receipt of molecularly matched therapy is associated with improved outcomes in patients with pancreatic cancer.
Treatment Options for Pancreatic Neuroendocrine Tumors
In the management of PNETs it is important to differentiate between functional and nonfunctional PNETs in order to determine the course of treatment.
Benefits of Insulin Plus Pramlintide in Artificial Pancreas Systems
A novel dual-hormone artificial pancreas system that delivers both rapid insulin and pramlintide was found to improve glucose control.
Natural Genetic Variation in a Calcium Channel Linked to Chronic Pancreatitis
Natural genetic variants in a calcium-selective ion channel gene, TRPV6, appear to influence early-onset chronic pancreatitis.
Multiple Factors Linked to Hospital Readmission Following Pancreatectomy
Results of this study showed no improvement in the rate of 30-day hospital readmission for patients with cancer undergoing pancreatectomy between 2005 and 2011.
Patients With Chronic Pancreatitis at Increased Risk for Diabetes Emergencies
Chronic pancreatitis is associated with increased risk for diabetes-associated emergencies, including diabetic ketoacidosis.
New Pancreaze Formulation Approved With Extended Shelf Life
The Food and Drug Administration has approved a new formulation of Pancreaze (pancrelipase; Vivus) Delayed Release Capsules which would allow for an extended shelf life of 36 months.
Addition of Pegilodecakin to FOLFOX Did Not Improve OS in Metastatic Pancreatic Cancer
Promising results from an earlier-phase study of FOLFOX plus pegilodecakin in metastatic PDAC refractory to gemcitabine provided a rationale for this study.
A Model for Predicting the Risk of Healthy Organ Exposure in Patients With Locally Advanced Pancreatic Cancer Treated With SBRT
Exceeding tolerances of healthy organs-at-risk as a result of daily anatomical deformations is a concern for patients with LAPC treated with SBRT.
Lynparza Gains Pancreatic Cancer Indication
The Food and Drug Administration (FDA) has approved Dayvigo (lemborexant; Eisai) for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance in adult patients.
No Link Found Between Hepatitis C Infection and Extrahepatic Cancers
A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.
Resection Should Be Considered Even in Certain Smaller pNETs
Patients who had tumors measuring 1.5 cm to 2 cm were at double the risk for lymph node metastasis.
Resistance to Immune Checkpoint Inhibition in Pancreatic Cancer
Research presented at SITC 2019 looks at 2 different mechanisms for resistance to immune checkpoint inhibition in pancreatic ductal adenocarcinoma.
Development of Validated Method to Assess, Characterize Pain Mechanisms in Chronic Pancreatitis
Pain phenotypes can be used in the future to attempt prediction of response to treatment in patients with painful chronic pancreatitis and thus provides a framework for personalized pain management.
Effects of Surgeon Volume, Nurse-to-Patient Ratio on Potential Complications With Pancreaticoduodenectomy
Although higher nurse-to-patient ratios ensure good outcomes for patients undergoing pancreaticoduodenectomy, PD-specific surgeon volume has a greater effect on risks of complications for these patients.
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