SAN ANTONIO — Numerous intestinal surgeries or massive resection frequently lead to short bowel syndrome (SBS) which is associated with repeated hospitalizations and has high morbidly and resource utilization. The rate of in-hospital mortality associated with SBS has decreased within the last decade despite a rise in SBS hospitalizations, according to study results presented at the 2019 American College of Gastroenterology (ACG) Annual Scientific Meeting and Postgraduate Course, held October 25 to 30, 2019, in San Antonio, Texas.

The objective of this study was to evaluate trends of SBS hospitalizations, mortality, and related costs. Researchers evaluated SBS cases during a 10-year period from 2005 to 2014 using the United States’ Nationwide In-patient Sample Database. Any cases labeled with ICD9 hospital discharge codes 579.3 and 99.15 were classified as SBS cases, as SBS does not have a unique diagnostic code.

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Results revealed there were 53,040 hospitalizations associated with SBS. SBS-related hospitalizations increased from 4037 to 6265 during the 10-year study period, though all-cause in-hospital mortality decreased from 40/1000 hospitalizations to 29/1000 hospitalizations. The most common comorbidities were protein-calorie malnutrition (n=13,063), hypertension (n=11,450), hypokalemia (n=11,334), acute kidney injury (n=10,611), and dehydration (n=9649), and 15,761 patients received packed red cell transfusion. The mean length of stay for SBS hospitalization was 14.7 days, and the average hospital cost was $31,921.

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The study researchers concluded that the number of SBS hospitalizations increased by 54% during the last 10 years while in-hospital SBS mortality decreased by 27.5%, and that additional research is needed to determine the causes of increased hospitalization and improved mortality.


Siddiqui MT, Singh A, Bilal M, Kirby DF. Epidemiology and healthcare resource utilization associated with adults hospitalized with short bowel syndrome. Poster presentation at: 2019 ACG Annual Scientific Meeting and Postgraduate Course; October 25-30, 2019; San Antonio, Texas. Abstract P1255.