In patients with chronic constipation, the most common form of anorectal dysfunction is Type 1 dyssynergic defecation.
The study researchers concluded that the number of SBS hospitalizations increased by 54% during the last 10 years while in-hospital SBS mortality decreased by 27.5%, and that additional research is needed to determine the causes of increased hospitalization and improved mortality.
In children with functional constipation, no clear improvement over placebo was observed for linaclotide; however, a trend for improved efficacy was observed at higher doses.
A recent report published in the journal Neuropsychobiology describes the case of a 34-year-old woman with major depressive disorder whose symptoms improved following the initiation of an elimination diet.
Severe micronutrient deficiency should be considered in the differential diagnosis in complex cases where a clear etiology is unknown.
High gluten intake during the first 5 years of life was a statistically significant, independent risk factor for both celiac disease (CD) autoimmunity and CD in genetically predisposed children.
The new safety information is based on interim results from an ongoing phase 2 trial.
Individuals who are obese or severely obese are more likely to have chronic diarrhea.
Researchers found approximately one-third of patients with type 1 diabetes and celiac disease were able to achieve sustained celiac-specific antibody negativity after celiac disease diagnosis.
Clinicians are encouraged to gain an understanding about when HLA genetic testing should be ordered, the type of test that should be ordered, and how to interpret results.
Endoscopic duodenal mucosal resurfacing was found to be safe, feasible, and very effective for improving glycemic control in patients with type 2 diabetes.
Increased gluten intake may increase celiac disease autoimmunity, celiac disease in at-risk children
Based on technical review and expert consensus, a guideline committee put together by the American Gastroenterological Association (AGA) released official recommendations on the laboratory evaluation of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D) in immunocompetent adults. This report was published in Gastroenterology. Members of the AGA guideline committee and authors of the technical review…