Fecal Microbiota Transplantation Superior to Fidaxomicin for Recurrent C Difficile Infection
Data from a study presents compelling evidence for the superiority of FMT in multiply recurrent CDI.
Other Bowel Disorders
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Risk for Gluten Exposure High With Specific School Activities
Specific common school activities, such as paper mâché and baking projects, pose a high risk for gluten exposure.
Pediatric Patients With Newly Diagnosed Celiac Disease Report Lower HRQOL
Pediatric patients with newly diagnosed celiac disease (CD) reported lower health-related quality of life (HRQOL) when compared with healthy children with nonceliac gastrointestinal (GI) complaints, according to a study published in the Journal of Pediatric Gastroenterology & Nutrition. CD is a common chronic condition associated with broad range of physical and psychosocial problems. In this…
Dual Therapy for Clostridioides difficile Infection Not Superior to Vancomycin Alone
Dual therapy with intravenous metronidazole and oral vancomycin is not superior to oral vancomycin alone in the treatment of Clostridioides difficile infections.
Does Continuous PPI Use Increase the Risk of Enteric Viral Infections?
An increased risk of acute gastroenteritis during winter epidemic periods was observed in patients 45 years and older on continuous PPI therapy.
Large Sample Sizes Needed for Infection Control Cluster-Randomized Trials
In the field of hospital epidemiology, there is a need for higher-quality trials that demonstrate more conclusive results, which in turn require larger sample sizes.
FDA: Do Not Use Products Distributed by Basic Reset, Biogenyx
Drugs, dietary supplements and devices from Basic Reset and Biogenyx have not been approved for any medical uses.
Social Risk Factors Associated With Post-Colectomy Surgical Site Infections
Infection prevention programs targeting low-income groups undergoing colectomy may be important in reducing surgical site infections.
High Tissue-Transglutaminase Antibody Titer Can Lead to Celiac Disease
High tTGA titer, female sex, hypothyroidism, and history of autoimmune disease are significant predictors for a diagnosis of celiac disease in adults.
FDA and GI Perspectives on Challenges, Controversies in Drug Safety Monitoring
The FDA plays a critical role in the evaluation of drug safety prior to approval and following introduction into clinical practice.
Colonoscopy Recommended After Diverticulitis to Identify Potential CRC
The rate of CRC after diverticulitis is significantly higher than the rate observed at screening colonoscopy, regardless of whether the disease is complicated, and that colonoscopy should be performed following diverticulitis diagnosis.
Helicobacter pylori Infection Must Be Wiped Out to Cut Gastric Cancer Risk
Only complete eradication of Helicobacter pylori infection, not treatment alone, will reduce the risk for developing stomach cancer.
After 2006 Elective Colectomy Guideline Change, Rates of Elective Colectomy Increases Continued
After the 2006 change in elective colectomy guidelines, rates of elective surgery for diverticulitis continued to increase in the United States, doubling among patients age 65 to 79 years.
New Emerging Viruses Causing Acute Gastroenteritis in Children With Hematopoietic Cell Transplant
The epidemiology of acute gastroenteritis pathogens identified from pediatric patients who have undergone allogenic hematopoietic cell transplant may be changing.
Fecal Microbiota Transplant Cuts Bloodstream Infection in Clostridioides difficile
Patients with recurrent Clostridioides difficile infection (CDI) who receive treatment with fecal microbiota transplantation (FMT) are less likely to develop a primary bloodstream infection (BSI) than those receiving antibiotics.
Factors Correlated to HRARM Findings in Chronic Constipation
In patients with chronic constipation, the most common form of anorectal dysfunction is Type 1 dyssynergic defecation.
In-Hospital SBS Mortality Has Decreased Despite Increased Hospitalizations
The study researchers concluded that the number of SBS hospitalizations increased by 54% during the last 10 years while in-hospital SBS mortality decreased by 27.5%, and that additional research is needed to determine the causes of increased hospitalization and improved mortality.
Linaclotide Safety and Efficacy in Pediatric Functional Constipation
In children with functional constipation, no clear improvement over placebo was observed for linaclotide; however, a trend for improved efficacy was observed at higher doses.
Food for Thought: Mood Improvements Following Dietary Modification
A recent report published in the journal Neuropsychobiology describes the case of a 34-year-old woman with major depressive disorder whose symptoms improved following the initiation of an elimination diet.
Persistent Diarrhea, Delirium, and Beefy Tongue: Is It Pellagra?
Severe micronutrient deficiency should be considered in the differential diagnosis in complex cases where a clear etiology is unknown.
Does High Gluten Intake During Childhood Increase Risk for Celiac Disease?
High gluten intake during the first 5 years of life was a statistically significant, independent risk factor for both celiac disease (CD) autoimmunity and CD in genetically predisposed children.
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