Global Prevalence of Functional Constipation According to the Rome Criteria
Researchers performed a systematic review and meta-analysis to estimate the global prevalence of functional constipation based on the Rome criteria.
Other Bowel Disorders
OTHER BOWEL DISORDERS
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Lenvatinib Beneficial for Health-Related Quality of Life in Unresectable Hepatocellular Carcinoma
In a post-hoc analysis, researchers assessed the effects of lenvatinib compared with sorafenib on health-related quality of life in patients with hepatocellular carcinoma.
Safety and Efficacy of Chinese Herbal Medicine for Treating Childhood Constipation
Investigators assessed the safety and efficacy of XiaojiDaozhi Decoction, a form of Chinese herbal medicine, in relieving childhood constipation.
Quality of Life Measures in Opioid-Induced Constipation: What Constitutes a Minimal Clinically Important Difference?
Researchers analyzed data from patients with chronic non-cancer pain and opioid-induced constipation to determine PAC-SYM and PAC-QOL minimal clinically important difference values.
Microscopic Colitis: New PPI Data
The exact pathophysiology of microscopic colitis is not completely understood, though PPIs and NSAIDs are 2 medications commonly implicated for triggering the inflammatory process.
Potential Association Between Celiac Disease and Autism Spectrum Disorder
Investigators attempted to analyze the link between celiac disease and autism spectrum disorder based on previously published research.
Abdominal Pain, Diarrhea in COVID-19 Linked to H pylori Infection
Researchers investigated the effects of H pylori on the clinical presentation and disease course of COVID-19 infections.
Rethinking the Role of Constipation in Diabetes
Constipation has long been thought of as a benign condition and one better suited for self-management, but if left untreated, it could lead to a host of other medical conditions, including cardiovascular disease, shows one study in this feature.
A Novel Endopeptidase Has Potential as an Oral Treatment for Patients With Celiac Disease
Researchers investigated the safety and efficacy of the novel endopeptidase TAK-062 for gluten degradation in patients with celiac disease and healthy controls.
TAK-101 May Prevent Gluten-Induced Immune Activation in Celiac Disease
Investigators analyzed the effects of TAK-101 from the induction of gliadin-specific T-cell tolerance in patients with biopsy-confirmed celiac disease.
Irritable Bowel Syndrome: What Your Patients Need to Know
Irritable bowel syndrome is rarely serious, but is still an inconvenience and a painful disorder for patients who have it. For patients who have IBS or are concerned they may have it, how can you explain the basics of how it is detected and managed?
Polyethylene Glycol With Electrolytes Safely Treats Constipation in Children Aged Less Than 2 Years
Investigators analyzed the usage and risk profile of PEG+E in children aged less than 2 years.
Diverticulitis: Amoxicillin-Clavulanate vs Metronidazole-with-Fluoroquinolone
Investigators examined the effectiveness of amoxicillin-clavulanate vs metronidazole-with-fluoroquinolone in outpatient diverticulitis treatment.
Elevated Serum CRP After Colorectal Surgery Predicts Anastomotic Leakage
As serum C-reactive protein (CRP) levels tend to rise in infective and inflammatory states, and elevated CRP has been linked to anastomotic leak (AL), these researchers conducted a meta-analysis of current CRP data in AL after colorectal surgery to find out more.
Amoxicillin-Clavulanate Effective for Outpatients With Diverticulitis
For immunocompetent patients with diverticulitis in the outpatient setting, amoxicillin-clavulanate is as effective as metronidazole with fluoroquinolone.
Exploring the Impact of Nutrition on the Gut Microbiome
The systemic effects of the gut microbiome persist throughout the life course, though neonatal and early-life disruptions may have the greatest consequences on gut health.
APPAC Trial: Uncomplicated Acute Appendicitis: Oral Antibiotics vs Intravenous Antibiotics?
Study authors compared oral moxifloxacin with combined intravenous ertapenem followed by oral levofloxacin in the managed of uncomplicated acute appendicitis.
Type 1 Diabetes With Celiac Disease Increases Depression Risk in Adolescents
Celiac disease is known to be associated with depression and anxiety in adults with type 1 diabetes and celiac disease. In this study, researchers examine the theory in adolescents with T1D and celiac disease.
Reflux Esophagitis Following Eradication of Helicobacter pylori-Positive Ulcer Disease
Investigators performed a cross-sectional study to assess reflux esophagitis in patients having undergone successful eradication of Helicobacter pylori infection.
Study Suggests Limited Efficacy of OTC Meds for Chronic Idiopathic Constipation
Results showed that the majority of patients expressed dissatisfaction with the effect of the OTC agent on constipation and CIC-specific abdominal symptoms.
Iron-Deficiency Anemia Secondary to Asymptomatic Celiac Disease: A Case Study
A 21-year-old woman presents with a complaint of continued iron deficiency despite treatment with oral iron supplementation.
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