Stool banks may guarantee reliable, timely and equitable access to fecal microbiota transplantation for patients and a traceable workflow that ensures safety and quality of procedures.
Patients with recurrent Clostridioides difficile infection (CDI) who receive treatment with fecal microbiota transplantation (FMT) are less likely to develop a primary bloodstream infection (BSI) than those receiving antibiotics.
As a part of the LIVERHOPE project, researchers evaluated the safety of 2 different simvastatin doses in combination with rifaximin vs placebo in patients with decompensated cirrhosis.
Among rhesus macaques, mother-reared infants more quickly acquired adult-typical microbiota and had higher levels of beneficial commensal taxa compared with Cesarean-delivered, human-reared, formula-fed infants.
Antibiotic therapy administered prior to treatment with ICIs was negatively associated with OS across tumor types, as well as tumor response, the researchers noted.
The researchers concluded that the use of oral antibiotics was associated with colorectal cancer, but the effect size and pattern of risk varied by anatomical location in the colorectum.
Cirrhosis and chronic liver disease are endemic in the veteran population. These conditions — often associated with alcohol and substance use or obesity — can be exacer-bated by posttraumatic stress disorder (PTSD). In turn, PTSD is often linked with great-er mortality from chronic liver disease.
The researchers discovered that while babies delivered vaginally received most of their gut bacteria from their mothers, babies delivered by cesarean birth did not. In addition, babies delivered by cesarean harbored more bacteria commonly associated with hospital.
Injecting mice with microbial antigens via adjuvant CpG oligodeoxynucleotides (CpG-ODN) and/or curdlan can induce antigen-specific mucosal and systemic immune responses that protect against microbe-associated intestinal diseases.
Infant nontoxigenic and toxigenic C difficile colonization may be linked to humoral immune responses that can provide protection against C difficile infection later in life.
The impact of eradicated Helicobacter pylori on the pediatric gastric microbial community structure shows restoration of bacterial diversity consistent with noninfected children in the same endemic region.
The use of levofloxacin as prophylaxis for the prevention of neutropenic fever and bloodstream infections was associated with less disruption of the gut microbiome in patients with hematologic malignancy.
Methanosphaera stadtmanae was significantly less frequent and in lower abundance in fecal samples of children with asthma compared with children without asthma.
![The clustering of RA among family members suggests a strong genetic link, supported by the identification of specific alleles within defined loci in the human leukocyte antigen (HLA) system that are associated with increased risk for the development of anticitrullinated protein antibody-positive and anticitrullinated protein antibody-negative RA. [3]](https://www.gastroenterologyadvisor.com/wp-content/uploads/sites/23/2019/09/thinkstockphotos15641636741_1010901.jpg)
