Investigational Lactose Intolerance Therapy Misses End Points in Phase 3 Trial
Ritter Pharmaceuticals announced that the phase 3 clinical trial of RP-G28 for lactose intolerance did not meet its primary or secondary end points.
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![The clustering of RA among family members suggests a strong genetic link, supported by the identification of specific alleles within defined loci in the human leukocyte antigen (HLA) system that are associated with increased risk for the development of anticitrullinated protein antibody-positive and anticitrullinated protein antibody-negative RA. [3]](https://www.gastroenterologyadvisor.com/wp-content/uploads/sites/23/2019/09/thinkstockphotos15641636741_1010901.jpg)
HLA Alleles With Risk for AS, RA Affect Gut Microbiome
Researchers examined the effects of HLA-B27 and HLA-DRB1 alleles on the intestinal microbiome of healthy individuals.
Model Estimates Effect of Probiotics on Costs for Flu-Like Illnesses
Probiotics could reduce the health care and economic burden of flu-like respiratory tract infections.
What Role Does Bariatric Surgery Play in Altering the Gut Microbiome?
Researchers are still elucidating how weight loss after bariatric surgery affects the gut microbiome and overall health.
Antigen-Specific Mucosal Immunity Protects Against Microbe-Associated Intestinal Diseases
Injecting mice with microbial antigens via adjuvant CpG oligodeoxynucleotides (CpG-ODN) and/or curdlan can induce antigen-specific mucosal and systemic immune responses that protect against microbe-associated intestinal diseases.
C difficile Colonization in Infants May Trigger Antitoxin Immune Response
Infant nontoxigenic and toxigenic C difficile colonization may be linked to humoral immune responses that can provide protection against C difficile infection later in life.
Gastric Microbiota Restoration Related to Eradication of Helicobacter pylori
The impact of eradicated Helicobacter pylori on the pediatric gastric microbial community structure shows restoration of bacterial diversity consistent with noninfected children in the same endemic region.
BMD in Osteoporosis Associated With Alterations in Abundance of Gut Microbiota
Researchers determined whether gut microbiota was associated with bone mineral density in individuals at high risk for reduced BMD and fractures.
Levofloxacin Prophylaxis Least Disruptive to Gut Microbiome in Patients With Hematologic Malignancy
The use of levofloxacin as prophylaxis for the prevention of neutropenic fever and bloodstream infections was associated with less disruption of the gut microbiome in patients with hematologic malignancy.
Sensitization to S aureus Enterotoxins May Increase Risk for Severe Asthma
Sensitization to Staphylococcus aureus enterotoxins was linked to an increased subsequent risk for severe asthma and asthma exacerbations.
Asthma and the Gastrointestinal Microbiome: Is There a Causative Link?
It has long been acknowledged by the medical community that there is some link between asthma and gastrointestinal symptoms.
Gut Microbiome Archaea May Influence Childhood Asthma Risk
Methanosphaera stadtmanae was significantly less frequent and in lower abundance in fecal samples of children with asthma compared with children without asthma.
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![The clustering of RA among family members suggests a strong genetic link, supported by the identification of specific alleles within defined loci in the human leukocyte antigen (HLA) system that are associated with increased risk for the development of anticitrullinated protein antibody-positive and anticitrullinated protein antibody-negative RA. [3]](https://www.gastroenterologyadvisor.com/wp-content/uploads/sites/23/2019/09/thinkstockphotos15641636741_1010901-150x150.jpg)