Patients with recurrent Clostridioides difficile infection (CDI) who receive treatment with fecal microbiota transplantation (FMT) are less likely to develop a primary bloodstream infection (BSI) than those receiving antibiotics.
Among rhesus macaques, mother-reared infants more quickly acquired adult-typical microbiota and had higher levels of beneficial commensal taxa compared with Cesarean-delivered, human-reared, formula-fed infants.
Cirrhosis and chronic liver disease are endemic in the veteran population. These conditions — often associated with alcohol and substance use or obesity — can be exacer-bated by posttraumatic stress disorder (PTSD). In turn, PTSD is often linked with great-er mortality from chronic liver disease.
The researchers discovered that while babies delivered vaginally received most of their gut bacteria from their mothers, babies delivered by cesarean birth did not. In addition, babies delivered by cesarean harbored more bacteria commonly associated with hospital.
Injecting mice with microbial antigens via adjuvant CpG oligodeoxynucleotides (CpG-ODN) and/or curdlan can induce antigen-specific mucosal and systemic immune responses that protect against microbe-associated intestinal diseases.
The impact of eradicated Helicobacter pylori on the pediatric gastric microbial community structure shows restoration of bacterial diversity consistent with noninfected children in the same endemic region.
The use of levofloxacin as prophylaxis for the prevention of neutropenic fever and bloodstream infections was associated with less disruption of the gut microbiome in patients with hematologic malignancy.