Microbiome

Latest News

Gut Microbiome: A New Mechanism to Monitor Response to Biologics?

By

Kwamesha Joseph

The gut microbiome is complex within irritable bowel disease (IBD), and its disruption may be a potential contributing factor in the pathogenesis of IBD.

How Can Safe and Effective Microbiome Drugs Be Developed?

By

Jessica Nye

To develop microbiome drugs, scientists will need to address challenges in safety, uniformity, and delivery.

Fecal Transplant May Counter Anti-PD-1 Resistance in Melanoma

Fecal microbiota transplantation together with anti-programmed cell death protein 1 therapy possibly may alter the gut microbiome and overcome resistance to anti-PD-1 in some patients with melanoma.

Exploring the Impact of Nutrition on the Gut Microbiome

By

Emily Pond

The systemic effects of the gut microbiome persist throughout the life course, though neonatal and early-life disruptions may have the greatest consequences on gut health.

Inflammatory Bowel Disease and Dementia: The Potential Risks

By

C. Andrew Kistler, MD, PharmD

A clinician discusses whether inflammatory bowel disease is a risk factor for the development of dementia.

IBD-Like Microbiome Observed in Healthy Co-twins

By

Colby Stong

Researchers evaluated the IBD-like microbiome signatures of healthy co-twins from IBD-discordant twin pairs to see whether these IBD-like microbiome signatures might precede the onset of IBD.

Assessment of the Salivary Microbiome With PPI Use for GERD

By

Vincent Soreca

Investigators sought to determine whether the presence of GERD was associated with a modified microbial profile in patients with untreated GERD and whether using proton pump inhibitors might result in a salivary microbiome that is further distinct.

Triple Therapy for Helicobacter pylori Eradication Safe for Adolescents

By

Jessica Nye, PhD

A team of investigators conducted a prospective, multicenter study to assess the safety of H pylori eradication therapy in adolescent students.

Gastrointestinal Infection Is Associated With Increased Risk of Microscopic Colitis

By

Colby Stong

A team of Swedish investigators conducted a case-control study to determine the relationship between gastroenteritis and risk of developing microscopic colitis.

Composition of Gut Microbiome Altered in Patients With COVID-19

The composition of the gut microbiome is altered in patients with COVID-19, with the perturbed composition correlating with disease severity.

Evidence Suggests Fecal Transplant Save, Effective for Clostridioides difficile Infections

By

Brandon May

The FMT National Registry, established by the AGA in partnership with other organizations, provides initial results on the safety and effectiveness of FMT for the management of Clostridioides difficile infections.

Bacterial and Fungal Profiles Estimate Infliximab Response in IBD

By

Virginia A. Schad, PharmD, RPh

A team of investigators sought to determine the influence of infliximab on gut bacterial and fungal composition in patients with inflammatory bowel disease.

Gluten-Free Diet Induces Changes in Intestinal Microbiota of Children With CD

By

Jessica Nye, PhD

Investigators characterized the gut microbiota of children with celiac disease to collect data on the determinants of the microbiota likely to change in children following a gluten-free diet.

Impaired Microbial Detoxification May Be Involved in ASD Pathogenesis

By

Colby Stong

Investigators used a quasi-paired cohort strategy to study how the microbiome, specifically microbial detoxification, might contribute to the pathogenesis of autism spectrum disorder.

Gut Microbiome Changes Different in AS and IBD, Associated With Disease Activity

By

Emily Pond

Researchers assessed whether the gut microbiome in ankylosing spondylitis and inflammatory bowel disease was different, and whether it correlated with disease activity.

Hydrogen, Methane, and Hydrogen Sulfide-Assessing Trio-Smart Test Hits Market

By

Rachel Narozniak, MA

Trio-SmartTM, a novel new breath test developed to measure hydrogen, methane, and hydrogen sulfide, is now available and can be ordered on the test’s website.

Probiotic Inhibits Viral Proliferation in Rotaviral Gastroenteritis

By

Brandon May

Investigators evaluated the safety and efficacy of Lactobacillus plantarum (LRCC5310), a probiotic organism, in children hospitalized with rotaviral gastroenteritis.

Diet Modifications Decrease Intestinal Inflammation in Diverticulitis

By

Virginia A. Schad, PharmD, RPh

While the etiopathogenesis of diverticulitis is not completely understood, recent evidence suggests that chronic inflammation and alterations in the gut microbiome may be key factors in the development of diverticulitis.

Multidisciplinary Care Improves Symptoms Best in Functional GI Disorders

By

Brandon May

Researchers compared integrated multidisciplinary clinical care vs gastroenterologist-only care with regard to symptoms, specific functional disorders, psychological state, quality of life, and cost of care for treating functional gastrointestinal disorders.

Gut Microbiome in Cirrhosis Linked to ACLF

By

Virginia A. Schad, PharmD, RPh

Researchers analyzed the relationship between an altered gut microbiome and complications of cirrhosis and survival and sought to determine its effect on disease progression and prognosis.