Metabolic Liver Disease

Latest Articles

Renaming and Redefining Pediatric Nonalcoholic Fatty Liver Disease

By

Jennifer Champagne, PharmD, RPh, BCPS

Publish Date October 22, 2021

An international panel proposed updated criteria for disease diagnosis, along with a more age-appropriate disease name and definition, for pediatric patients with NAFLD.

Red Meat Intake Associated With Nonalcoholic Fatty Liver Disease

By

Vincent Soreca

Publish Date October 20, 2021

Investigators assessed the association between meat intake and risk for nonalcoholic fatty liver disease in a study cohort with low overall consumption of red meat.

Insights on Improving Care for Patients With NAFLD/NASH

By

Vincent Soreca

Publish Date October 1, 2021

The American Gastroenterological Association offered strategies for clinical practice, future research, and policy agenda for the treatment of patients with NAFLD and NASH.

Sleep-Wake Disturbance Highly Prevalent in Populations With Liver Disease

By

Vincent Soreca

Publish Date September 24, 2021

Researchers summarized the reciprocal interaction between sleep and liver diseases, including cirrhosis, and investigated potential approaches for therapeutic interventions.

Novel Gene Therapy for Wilson Disease Gets Fast Track Status

By

Brian Park, PharmD

Publish Date August 20, 2021

VTX-801 is an investigational, novel rAAV-based gene therapy that delivers a shortened version of the ATP7B transgene.

Better Strategies Needed for Managing NAFLD in Adults

Publish Date July 28, 2021

Effective screening, diagnosis, and management strategies are needed for patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Sequential Combination of Markers May Help Reduce Need for Liver Biopsies in NAFLD

By

Colby Stong

Publish Date July 26, 2021

Investigators conducted an individual patient data meta-analysis to assess the LSM-VCTE and compare it with the FIB-4 and NFS scores in order to develop diagnostic strategies that could reduce the need for liver biopsies.

Adipose Tissue and the Pathogenesis of Insulin Resistance in Patients with Obesity and NAFLD

By

Virginia A. Schad, PharmD, RPh

Publish Date July 19, 2021

Researchers investigated the underlying mechanisms responsible for insulin resistance in patients with obesity and NAFLD.

Severe NAFLD Associated With High Subclinical Atherosclerosis Risk

By

Lauren Biscaldi

Publish Date July 19, 2021

The goal of this study was to determine the relationship between subclinical coronary artery disease and the severity of nonalcoholic fatty liver disease.

A Holistic, Multidisciplinary Approach Needed for the Management of Comorbidities Among Patients With Nonalcoholic Fatty Liver Disease

By

Jessica Nye, PhD

Publish Date June 24, 2021

Researchers reviewed the comorbidities associated with NAFLD across body systems and offered suggestions for facilitating a multidisciplinary care approach for these patients.

Noninvasive Means of Identifying Patients With High-Risk Nonalcoholic Fatty Liver Disease

By

Emily Pond

Publish Date June 22, 2021

Investigators aimed to identify patients with high-risk NAFLD using noninvasive methods and link them to appropriate care.

NAFLD in Lean Patients May Be Linked to Metabolic Syndrome, Cardiovascular Risk

By

Rita Aghjayan

Publish Date June 21, 2021

Investigators aimed to determine the metabolic and cardiovascular phenotypes of lean patients with NAFLD.

SGLT2i and GLP-1RA May Improve Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus

By

Vincent Soreca

Publish Date May 25, 2021

Investigators examined the safety and efficacy of SGLT2i and GLP-1RA on treatment of nonalcoholic fatty liver disease in type 2 diabetes mellitus.

Serum Cardiac Biomarkers May Indicate Increased Risk for Severe Coronary Artery Disease Among Patients With Nonalcoholic Fatty Liver Disease

By

Jessica Nye, PhD

Publish Date May 25, 2021

Researchers assessed cardiac biomarkers, among other clinical factors, associated with severe CAD in patients with NAFLD.

Moderate-Intensity Aerobic Training and Resistance Training With Dietary Modification Equally Beneficial for NAFLD

By

Colby Stong

Publish Date May 12, 2021

Investigators compared the effects of moderate-intensity aerobic vs resistance exercise with dietary modifications in patients with NAFLD.

Bariatric Surgery Reduces Cancer Risk in Patients with Nonalcoholic Fatty Liver Disease and Obesity

By

Emily Pond

Publish Date April 23, 2021

Investigators examined the effects of bariatric surgery on cancer risk in patients with NAFLD and severe obesity.

Bariatric Surgery Cuts Cancer Risk With Obesity + Liver Disease

Publish Date April 19, 2021

Bariatric surgery is associated with significant reductions in the risks for any cancer and obesity-related cancer in nonalcoholic fatty liver disease patients with severe obesity.

NASH—A Global Problem in Need of Better Diagnostic Tests and Treatments

By

Colby Stong

Publish Date April 9, 2021

Investigators summarized past and current research on the diagnosis and treatment of NASH to encourage development of noninvasive testing for the disease.

Increased Prevalence of Metabolic Dysfunction-Associated Fatty Liver Disease in Overweight, Obese Adults

By

Vincent Soreca

Publish Date March 8, 2021

A team of investigators conducted a study to estimate the global prevalence of metabolic dysfunction-associated fatty liver disease in overweight and obese adults.

African Americans Have Less NASH, Advanced Fibrosis Relative to White Patients With NAFLD

By

Virginia A. Schad, PharmD, RPh

Publish Date February 23, 2021

A team of investigators sought to better understand the interethnic clinical, biochemical, and histologic differences in the prevalence of NAFLD and NASH.