Improved Guidance Needed for Prophylactic Drain Placement After Hepatectomy
Prophylactic drains are commonly inserted during both major and minor hepatectomy procedures.
Liver
LIVER
Latest Articles
Hepatic Steatosis in People With HIV, People who Use Intravenous Drugs
Patients with HIV and those with a history of intravenous drug use may have significantly higher rates of hepatic steatosis.
Are Glycemic Measures in the Nondiabetic Range Linked to NAFLD?
Increased blood glucose levels, even within the nondiabetic range, are associated with increased risk for nonalcoholic fatty liver disease.
Epclusa Approved for Pediatric Patients with Chronic Hepatitis C Infection
Epclusa is a fixed-dose combination of sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor.
Increases in Primary Liver Cancer Cases Noted From 1990 to 2017
From 1990 to 2017, there were increases in the number of primary liver cancer cases among those diagnosed at ages 30 to 59 and ≥60 years.
Perioperative Management of Patients With Cirrhosis
The challenges associated with managing cirrhosis in patients undergoing non-hepatic surgery specifically are discussed.
Hepatic Cirrhosis Exacerbation Linked to Hospital Admission for Epilepsy
In patients with a known diagnosis of cirrhosis, hepatic exacerbations may increase the risk for hospitalization for epilepsy and status epilepticus.
HCC Risk Lower With Higher Intake of Vegetable Fats, Polyunsaturated Fats
The source of fats in an individual’s diet may alter the risk of developing hepatocellular carcinoma.
Alcohol-Induced Death Rates Increasing in the United States
From 2000 to 2016, there were large increases in alcohol-induced death rates across age and racial/ethnic subgroups.
Ultrasound May Identify Children at Risk for Cystic Fibrosis Liver Disease
A heterogeneous pattern on ultrasound examination of the liver may help identify children with cystic fibrosis at increased risk for developing advanced CF liver disease.
Noninvasive Markers of Liver Disease May Predict Complications in Diabetes
With the use of age-adjusted thresholds for noninvasive markers of liver steatosis and fibrosis, patients with type 2 diabetes may be referred more efficiently to specialists.
Noninvasive Scoring Systems May Identify Those at Risk for Severe Liver Disease
Noninvasive scoring systems have modest predictive ability to identify the future development of severe liver disease in patients in the general population.
QoL Extended With Atezolizumab + Bevacizumab in Liver Cancer
For patients with unresectable hepatocellular carcinoma, the combination of atezolizumab and bevacizumab is associated with longer time to deterioration of patient-reported quality of life.
High Rates of SVR Attained With Coblopasvir Plus Sofosbuvir for HCV Infection
In China, researchers investigate the sustained virologic response and safety profile of coblopasvir plus sofosbuvir taken once daily for 12 weeks among patients with HCV genotypes 1, 2, 3, or 6 infections, including individuals with compensated cirrhosis.
Consensus Report for Antiviral Resistance Testing of Hepatitis C Infections
The Public Health England Hepatitis C Virus Resistance Group recommended testing resistance for treatment of the hepatitis C virus by using a genotypic testing method of either the Sanger sequencing or next-generation sequencing methods.
Active Hepatocellular Carcinoma as a Risk Factor for DAA Treatment Failure
Intolerance to treatment with direct acting antiviral treatment was found to be associated with older age and advanced liver disease in patients with hepatocellular carcinoma.
Tumor Size, Stiffness May Be Relevant Biomarkers of Response to ICIs in HCC
The median change in HCC tumor size between responders and nonresponders was statistically significant.
Increasing US Emergency Department Visits Associated With HCV
As emergency departments (EDs) are critical settings for hepatitis C care in the United States, investigators evaluated trends and characteristics of hepatitis C-associated ED visits from 2006 to 2014.
Atezolizumab + Bevacizumab Prolongs Maintenance of QoL vs Sorafenib in Certain Patients With HCC
In this study, deterioration in specific PROs required a drop of at least 10 points from baseline.
Feasibility of Using HCV-Positive Organs for Heart Transplantation
In a small patient cohort, researchers found that heart transplantation from donors who were hepatitis C virus-positive to recipients without the virus were successful.
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