Polygenic Risk Score Comprises 12 Variants Capable of Predicting Risk of Cirrhosis
A team of investigators created a polygenic score that could identify a subset of the population at increased risk of developing cirrhosis.
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Use of Direct Acting Antivirals With Potent Inducers Examined in Case Series
While DAAs have improved the treatment of chronic HCV infection by eliciting higher rates of sustained virologic response, they also interact with a number of agents that could potentially limit their effectiveness.
Despite Diagnosis, Many HCV-Positive Liver Allograft Donors Healthier, Younger
Increased utilization of HCV-positive liver allografts for LT is seen as one of the ways to counter national organ shortages, so researchers set out to better characterize the allografts that come from HCV-positive donors from specific regions.
Neighborhood Deprivation Predicts Poorer Pediatric Liver Transplant Outcomes
A team of researchers sought to determine whether neighborhood deprivation affected outcomes in pediatric patients having undergone hepatic transplantation.
Validation of Fatty Liver Scoring Systems for the Diagnosis of NAFLD in Adolescents
A team of investigators sought to identify the accuracy of diagnostic tools for the detection of nonalcoholic fatty liver disease in adolescent patients.
Autoimmune Hepatitis Linked to Complications in Pregnant Women
In their presentation at The Liver Meeting, a team of investigators from the University of California, San Francisco sought to assess pregnancy outcomes in women with autoimmune hepatitis.
Lifestyle Modification for NAFLD: An AGA Clinical Practice Update
The American Gastroenterological Association commissioned an expert review to identify best practice advice for treating patients with nonalcoholic fatty liver disease.
Intra-State Differences in Liver Disease-Related Mortality in the US
Investigators sought to identify factors at the US county level that contribute to liver-related mortality.
Beta-Blocker Therapy Associated With Improved Outcomes in Advanced Chronic Liver Disease
A team of investigators sought to assess the impact of treatment with beta-blockers on systemic inflammation in individuals with advanced chronic liver disease.
Factors Contributing to Increased COVID-19 Risk in Blacks, Hispanics With Chronic Liver Diseases
A team of investigators sought to determine the impact of social and economic inequities on racial and ethnic minority individuals with chronic liver disease and COVID-19.
Bacterial Infections, Severe Alcoholic Hepatitis Affect Course of Decompensated Cirrhosis
An international team of investigators conducted a multicenter, prospective, observational study to identify factors contributing to acute decompensation of cirrhosis.
USPSTF Recommends Hepatitis B Screening for At-Risk Teens, Adults
The US Preventive Services Task Force concludes that screening adults and adolescents at increased risk for hepatitis B virus infection has moderate net benefit.
Semaglutide Found to Increase Rate of NASH Resolution
Investigators tested the safety and efficacy of the glucagon-like peptide-1 receptor agonist semaglutide in patients with nonalcoholic steatohepatitis and liver fibrosis.
Liver Grafts From Donors With DM Associated With Poor Outcomes After Transplant
Investigators of the national study compared early postoperative outcomes of patients who received liver grafts from donors with diabetes mellitus (DM) vs those who received grafts from donors without DM.
Hepatitis C Testing and Identification Sharply Declined During COVID-19 Pandemic
The COVID-19 systematic emergency response has led to a decrease in hepatitis C virus testing and identification.
Superior Outcomes Seen With Personalized Versus Standard Dosimetry Approach in HCC
Investigators compared the efficacy of a personalized dosimetry method targeting the index lesion with the standard approach targeting the perfused lobe.
HCC May Present at Earlier Stage of Liver Disease in Black Patients With HCV
Investigators evaluated the incidence of HCC in the absence of cirrhosis in Black patients with HCV.
Carbohydrate-Restricted Diet Reduces Hepatic Triglyceride Content in Children With NAFLD
Investigators compared a carbohydrate-restricted diet with a low-calorie diet to determine which more effectively reduced hepatic triglyceride content in children with nonalcoholic fatty liver disease.
Cirrhosis Cases Rising Among Women in North America
The researchers found the median age at diagnosis was 57 years, with cirrhosis etiology most commonly resulting from nonalcoholic fatty liver disease.
Bariatric Surgery Induces NASH Resolution Without Worsening Fibrosis
Investigators evaluated the long-term efficacy of bariatric surgery for patients with non-alcoholic steatohepatitis.
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