Irritable Bowel Syndrome (IBS)

Latest News

Upadacitinib Meets Endpoints in Ulcerative Colitis Maintenance Trial

By

Brian Park, PharmD

A significantly greater proportion of patients treated with upadacitinib 15mg and 30mg achieved clinical remission at week 52 compared with those receiving placebo.

Bacterial Biofilms Frequently Identified During Endoscopy Among Patients With IBS or UC

By

Jessica Nye, PhD

Researchers analyzed the presence and effect of mucosal biofilms in patients with irritable bowel syndrome and ulcerative colitis.

Treatments for Somatization and Functional Disability Improve QOL in Children With IBS

By

Virginia A. Schad, PharmD, RPh

Researchers compared the associations between abdominal pain and psychosocial distress with health-related quality-of-life in children with IBS.

Low FODMAP Diet and IBD: A Potential Option?

By

C. Andrew Kistler, MD, PharmD

Current research indicates that short-term utilization of an LFD may help ameliorate some mild IBS symptoms associated with quiescent IBD, while further long term studies are still needed.

Heartburn in Pediatric GI Disorders Associated with Psychiatric, Sleep Disturbances

By

Emily Pond

Researchers investigated the relationship between heartburn in pediatric patients and sleep disturbances, as well as psychiatric symptoms.

A Smartphone Application-Assisted Dietary Intervention Improves Symptoms of IBS, QoL

By

Jessica Nye, PhD

Researchers evaluated the effects of a low FODMAP diet delivered via smart phone vs standard otilonium bromide treatment in patients with IBS.

Assessing Impact of Individual FODMAPs on IBS Symptom Severity

By

Emily Pond

Researchers analyzed the effects of individual FODMAPs on symptom severity in patients with IBS.

Successful Management of IBS Symptoms Depends on Motivation, Social Support, Treatment Expectancy

By

Jessica Nye, PhD

Researchers attempted to identify actionable variables that impact therapeutic alliance in patients with IBS.

Assessing Impact of Individual FODMAPs on IBS Symptom Severity

By

Emily Pond

Researchers analyzed the effects of individual FODMAPs on symptom severity in patients with IBS.

Placebo Response Rate for Pharmacological Trials for IBS

By

Virginia A. Schad, PharmD, RPh

Researchers sought to determine the magnitude of placebo response rates and their contributing factors in clinical trials for irritable bowel syndrome.

Study Explores Links Between Diet, Gut Microbiome, and Inflammation

Diet directly impacts the gut microbiome, which directly affects inflammatory responses in the gut.

Irritable Bowel Syndrome: What Your Patients Need to Know

By

Steve Fiorillo

Irritable bowel syndrome is rarely serious, but is still an inconvenience and a painful disorder for patients who have it. For patients who have IBS or are concerned they may have it, how can you explain the basics of how it is detected and managed?

Gut Microbiome: A New Mechanism to Monitor Response to Biologics?

By

Kwamesha Joseph

The gut microbiome is complex within irritable bowel disease (IBD), and its disruption may be a potential contributing factor in the pathogenesis of IBD.

OLP vs DBP in Treatment of IBS

By

Colby Stong

Investigators compared the efficacy of open-label placebo with double-blind placebo in the treatment of patients with IBS.

Family History of IBS Linked to Psychological Disorders in Pediatric IBS

By

Vincent Soreca

Although people with IBS are known to be at increased risk for anxiety and depression, few studies to date have focused on the influence of family history on children with IBS.

ACG Provides Clinical Guideline on Irritable Bowel Syndrome

By

Colby Stong

The American College of Gastroenterology created guidelines to provide clinicians with evidence supporting the optimal management of patients with irritable bowel syndrome.

Novel Association Identified Between Brachyspira and IBS With Diarrhea

By

Virginia A. Schad, PharmD, RPh

A team of investigators sought to identify potential links between gut microbes and symptoms of irritable bowel syndrome.

Patients With Functional Dyspepsia May Be at Increased Risk for SIBO

By

Virginia A. Schad, PharmD, RPh

Investigators evaluated the prevalence of small intestinal bacterial overgrowth (SIBO) in a well-defined cohort of patients with functional dyspepsia (FD) using quantitative microbiological assessment of the duodenal aspirate.

Increasing GI Symptoms Seen in Approximately One-Third of Young Adults

By

Jessica Nye, PhD

Investigators sought to identify common GI symptoms in a large sample of “emerging adults” using the Patient-Reported Outcomes Measurement Information System – GI (PROMIS-GI) symptom scales.

Functional Constipation and IBS More Common in Pediatric Celiac Disease

By

Amit Akirov, MD

Celiac disease in children leads to an increased risk for functional constipation and irritable bowel syndrome compared with healthy controls.