Based on technical review and expert consensus, a guideline committee put together by the American Gastroenterological Association (AGA) released official recommendations on the laboratory evaluation of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D) in immunocompetent adults. This report was published in Gastroenterology. Members of the AGA guideline committee and authors of the technical review…
Probiotics should only be recommended for specific patient populations since there is not enough evidence to support their use in the majority of digestive conditions, according to new clinical guidelines released by the American Gastroenterological Association (AGA) and recently published in Gastroenterology.
A commonly used over-the-counter treatment for IBS is peppermint oil. The exact mechanism of action in IBS is not entirely known; however, it has been postulated that it may be mediated through smooth muscle relaxation, antimicrobial effects, modulation of pain receptors, and 5-hydroxytryptamine antagonism.
The researchers concluded that this is the first study to investigate the mucosa-associated gut microbiome in an adult population-based cohort and that no distinct microbial signature was observed in IBS.
Oral supplementation with 2 unique forms of human milk oligosaccharides can provide nutritional support that significantly reduces abnormal stool consistency, abdominal pain, and bloating and improves health-related quality of life in patients with IBS of all subtypes.
Zinc deficiency may perpetuate the underlying pathophysiology of IBS as well as associated psychiatric conditions, via the role zinc plays in the “brain-gut” axis, the immune system, and gastrointestinal barrier integrity.