Irritable Bowel Syndrome (IBS)

Latest News

Psychological Therapies for IBS

By

Tori Rodriguez, MA, LPC, AHC

Given the close relationship between IBS and mental health, the use of psychological modalities represents a growing area of interest in IBS management.

Assessment of Antispasmodics Available in North America for the Treatment of Chronic Abdominal Pain

By

Vincent Soreca

Researchers reviewed and summarized the safety and efficacy of individual antispasmodics available in North America for the treatment of chronic abdominal pain.

Tegaserod Safe, Effective for IBS-C in Women Aged Less Than 65 Years Without CVI Events

By

Vincent Soreca

Investigators assessed the safety and efficacy of tegaserod in women with IBS-C aged less than 65 years without a history of cardiovascular ischemic events.

Abdominal Pain and Depression Lead to Increased Health Care Use in Patients With Functional Bowel Disorders

By

Colby Stong

Investigators aimed to identify predictors of health care utilization in patients with irritable bowel syndrome, functional constipation, and functional diarrhea.

Gut Virome Is Stable Over Time But Varies in Subsets of Patients With IBS

By

Colby Stong

Researchers assessed the stability of the virome over time, the effect of diet and genetics, the impact of the virome on host gene expression, and whether specific viruses are associated with IBS subtypes.

Number of Psychological Comorbidities Linked to Worsening IBS Prognosis

By

Rita Aghjayan

Investigators aimed to determine whether a higher number of psychological comorbidities at baseline would exacerbate IBS prognosis in patients with Rome IV-defined IBS.

Linzess Labeling Updated Based on New Pediatric Data

By

Diana Ernst, RPh

The updated label now states that the treatment is contraindicated in patients less than 2 years of age due to the risk of serious dehydration.

A Multifactorial Approach to Treating IBS

By

Jennifer Champagne, PharmD, RPh, BCPS

Researchers provided practical tips and management approach strategies for the treatment of severe irritable bowel syndrome.

Psychotropic Drugs May Significantly Reduce Chronic Pain in Pediatric Patients

By

Jessica Nye, PhD

Study authors conducted a meta-analysis of randomized controlled trials to study the effectiveness of psychotropic medications in children and adolescents with chronic pain.

Separating Fact From Fallacy in Celiac Disease

By

Vincent Soreca

Clinicians summarized the current research and clarified widespread misinformation on celiac disease.

Tenapanor Effective for IBS-C

By

Colby Stong

Investigators assessed the long-term safety and efficacy of tenapanor for the treatment of patients with IBS-C.

Vitamin D Supplementation Does Not Improve Symptoms in IBS

For patients with irritable bowel syndrome (IBS), vitamin D supplementation has no impact on improving symptom severity or quality of life.

Upadacitinib Meets Endpoints in Ulcerative Colitis Maintenance Trial

By

Brian Park, PharmD

A significantly greater proportion of patients treated with upadacitinib 15mg and 30mg achieved clinical remission at week 52 compared with those receiving placebo.

Bacterial Biofilms Frequently Identified During Endoscopy Among Patients With IBS or UC

By

Jessica Nye, PhD

Researchers analyzed the presence and effect of mucosal biofilms in patients with irritable bowel syndrome and ulcerative colitis.

Treatments for Somatization and Functional Disability Improve QOL in Children With IBS

By

Virginia A. Schad, PharmD, RPh

Researchers compared the associations between abdominal pain and psychosocial distress with health-related quality-of-life in children with IBS.

Low FODMAP Diet and IBD: A Potential Option?

By

C. Andrew Kistler, MD, PharmD

Current research indicates that short-term utilization of an LFD may help ameliorate some mild IBS symptoms associated with quiescent IBD, while further long term studies are still needed.

Heartburn in Pediatric GI Disorders Associated with Psychiatric, Sleep Disturbances

By

Emily Pond

Researchers investigated the relationship between heartburn in pediatric patients and sleep disturbances, as well as psychiatric symptoms.

A Smartphone Application-Assisted Dietary Intervention Improves Symptoms of IBS, QoL

By

Jessica Nye, PhD

Researchers evaluated the effects of a low FODMAP diet delivered via smart phone vs standard otilonium bromide treatment in patients with IBS.

Assessing Impact of Individual FODMAPs on IBS Symptom Severity

By

Emily Pond

Researchers analyzed the effects of individual FODMAPs on symptom severity in patients with IBS.

Successful Management of IBS Symptoms Depends on Motivation, Social Support, Treatment Expectancy

By

Jessica Nye, PhD

Researchers attempted to identify actionable variables that impact therapeutic alliance in patients with IBS.