Inflammatory Bowel Diseases (IBD)
Inflammatory Bowel Diseases
Feature Article
Exclusive Enteral Nutrition Significantly Alters Gut Microbiota in IBD
Crohn disease and ulcerative colitis comprise the 2 primary subtypes of inflammatory bowel diseases (IBD). IBD currently has no known cure and whose pathogenesis is not well understood. However, an increasing amount of research points to genetic risk factors combined with antibiotic use and changes in intestinal microbiota as triggers for the onset of IBD.1,2…
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Deficits in Geriatric Assessment Prevalent in Seniors With Inflammatory Bowel Disease
Older patients with inflammatory bowel disease (IBD) have high prevalence of deficits in geriatric assessment.
Originator and Biosimilar SB5-Adalimumab Show Comparable Long-Term Effectiveness in Crohn Disease
Investigators sought to assess the effectiveness of SB5-adalimumab over 52 weeks in patients with Crohn disease after switching from originator-adalimumab.
Pregnant, Lactating Women Underrepresented in IBD Clinical Trials
Investigators assessed disparities in IBD clinical trials regarding a lack of inclusion of pregnant, lactating women; older adults; and racial and ethnic minorities.
Non-Anti-TNF-a Antibody Therapies Effective as Second-Line Treatment for Ulcerative Colitis
Investigators examined whether a patient’s initial response to anti-tumor necrosis factor (TNF)-a antibody could inform subsequent treatment in ulcerative colitis.
Are Live Vaccines Safe for Infants Exposed to Infliximab During Parent’s IBD Treatment?
Cosby A. Stone, MD, and Brigid S. Boland, MD, discuss the controversy of administering live vaccines to infants who were exposed to TNFi during pregnancy and breastfeeding.
Predicting Postoperative Fentanyl Use in Patients With Inflammatory Bowel Disease
Researchers sought to identify factors that could help predict postoperative opioid consumption in patients with IBD.
High Prevalence of Fatigue in Adults With Inflammatory Bowel Disease
Adults with inflammatory bowel disease (IBD) have a high prevalence of fatigue.
Early Anti-TNF Therapy Helps Reduce Health Care Utilization in Crohn Disease
Researchers compared the difference in overall health care utilization in patients with IBD who started anti-TNF therapy 2 years vs more than 2 years postdiagnosis.
Psychological Factors Determine Poor Prognostic Outcome in IBD
For adults with inflammatory bowel disease (IBD), psychological factors are an important determinant of poor prognostic outcome.
What Intestinal Infections Can Reveal About Celiac Disease and IBD Characteristics
Researchers sought to identify the clinical factors of inflammatory bowel disease and celiac disease that are associated with receiving a positive stool GIPCR test.
Pediatric-Onset IBD Associated With Increased Cancer Risk
A team of researchers analyzed the relative rate of cancer among children with inflammatory bowel disease.
Adalimumab Associated With Clinical Remission Beyond 1 Year in Pediatric Crohn Disease
Investigators analyzed adalimumab’s long-lasting clinical remission, associations of trough concentration, and linear growth in pediatric patients with Crohn disease.
Histologic Remission With NHI Effective for Predicting Relapse-Free Survival in Ulcerative Colitis
A team of researchers assessed histologic activity in patients with ulcerative colitis who were in endoscopic and clinical remission, using the NHI score to predict future relapse.
How Prevalent Is Polypharmacy Among Patients With Inflammatory Bowel Disease?
Researchers sought to determine the prevalence of polypharmacy in adults with Crohn disease and ulcerative colitis, collectively referred to as IBD.
Does Higher Adalimumab Induction and Maintenance Dosing Lead to Remission in Ulcerative Colitis?
Researchers examined the efficacy of higher adalimumab induction and maintenance dose regimens in adults with ulcerative colitis.
A Patient Classification System for Perianal Fistulizing in Crohn Disease
Researchers developed a classification system for identifying patients with perianal fistulizing Crohn disease and recommended treatment strategies.
How Is Simplified Magnetic Resonance Index of Activity Useful in Pediatric Crohn Disease?
Researchers assessed the association between simplified magnetic resonance index of activity and IC-measured inflammation levels in children with Crohn disease.
Ustekinumab Safe, Effective for Refractory Crohn Disease as Short- and Long-Term Therapy
Researchers evaluated the safety and efficacy profile of short- and long-term treatment with ustekinumab for patients with Crohn disease.
A Machine-Learning-Based Predictor for Histological Remission in Ulcerative Colitis
Researchers sought to create a histological index that would help evaluate inflammation and predict clinical outcomes in patients with ulcerative colitis.
Is Inflammatory Bowel Disease Care Entering an Era of Disease Modification Treatment?
A special issue of the Gastroenterology journal explores the future of treatment for inflammatory bowel diseases like Crohn disease and ulcerative colitis.
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