Inflammatory Bowel Diseases (IBD)

Latest News

Anxiety and Depression Common in Patients With Inflammatory Bowel Disease

By

Colby Stong

Researchers assessed the prevalence of symptoms of anxiety and depression in adult patients with irritable bowel disease.

Upadacitinib Meets End Points in Ulcerative Colitis Trial

By

Brian Park, PharmD

The U-ACCOMPLISH induction study evaluated the efficacy and safety of upadacitinib in 515 adults with moderate to severe ulcerative colitis.

Low Rates of GI-Related Adverse Events in Patients With PsA and AS Initiating Secukinumab

By

Amit Akirov, MD

Researchers evaluated gastrointestinal-related adverse events in patients with psoriatic arthritis and ankylosing spondylitis who were initiating secukinumab.

SARS-CoV-2 Vaccination Recommended for Patients With Inflammatory Bowel Disease

By

Colby Stong

The British Society of Gastroenterology IBD section and IBD Clinical Research Group has released a position statement on SARS-CoV-2 vaccination guidelines for patients with IBD.

Current Treatments for Patients With Inflammatory Bowel Diseases Experiencing Extraintestinal Manifestations

By

Jessica Nye, PhD

Researchers summarized the current knowledge on treatment options for extraintestinal manifestations in patients with IBD, while calling attention to gaps in the research.

Unexplained Gastrointestinal Disorders Remain Relatively Stable in a Specific Population Over 20 Years

By

Jessica Nye, PhD

Researchers analyzed the trends and prevalence of chronic, unexplained GI symptoms in a single community over a 20 year span.

Opioids and IBD: Current Challenges

By

C. Andrew Kistler, MD, PharmD

Initiation of opioid use during a flare of symptoms can eventually lead to chronic opioid use (COU), which can have detrimental effects on a patient’s IBD, as well as their overall clinical health.

Anti-SARS-CoV-2 Antibody Responses Attenuated in Patients Treated with Infliximab

By

Virginia A. Schad, PharmD, RPh

Researchers investigated whether infliximab-treated patients with inflammatory bowel disease have attenuated serological responses to SARS-CoV-2 infections.

Assessment of IBD Medications on COVID-19 Outcomes

By

Vincent Soreca

Researchers sought to assess the association of IBD medications and their combinations on the risk of severe COVID-19 outcomes.

Induction Therapy for Ulcerative Colitis with ABX464 is Safe and Well Tolerated

By

Virginia A. Schad, PharmD, RPh

Researchers conducted a phase 2a study to determine the safety and efficacy of ABX464 in patients with moderate to severe ulcerative colitis.

Depression and Gastrointestinal Symptoms Linked to Inflammatory Bowel Disease

By

Vincent Soreca

Researchers investigated whether psychological comorbidities predated the diagnosis and propagation of inflammatory bowel disease.

Disparities in the Diagnosis and Management of IBD Among Different Racial and Ethnic Groups

By

Vincent Soreca

Researchers sought to identify disparities in the care and outcomes of patients with IBD of differing races and ethnicities, in order to improve health care equity.

Primary Sclerosing Cholangitis and Colitis Leads to Increased Risk for Pouchitis

By

Virginia A. Schad, PharmD, RPh

Investigators compared rates of pouchitis and pouch failure among patients with and without primary sclerosing cholangitis.

Pediatric Crohn Disease Linked to Low Bone Mineral Density

By

Vincent Soreca

Researchers examined the effects of nutritional therapy on bone health in pediatric patients with Crohn Disease.

HIV and Inflammatory Bowel Disease: A Unique Patient Population

By

C. Andrew Kistler, MD, PharmD

The authors review gut dysfunction and microbiota changes during HIV infection and IBD and discuss how they may induce a dysfunctional mucosal barrier, dysbiosis, and changes on the cellular level, including monocytes, macrophages, and dendritic cells.

Laparoscopic Strictureplasty: A Safe, Feasible Treatment for Complicated Crohn Disease

By

Emily Pond

Investigators sought to determine the safety and feasibility of conventional and non-conventional laparoscopic strictureplasties for the treatment of Crohn Disease.

Tofacitinib Is Safe and Effective for Treatment of Severe Ulcerative Colitis

By

Jessica Nye, PhD

Researchers analyzed the effectiveness of tofacitinib for the treatment of moderate to severe ulcerative colitis.

Overview of Crohn Disease Management Following Gastrointestinal Cancer Onset

By

Vincent Soreca

Reviewers provided an overview of evidence for appropriate diagnostic pathway and management of Crohn disease following GI cancer onset.

Collagenous Colitis Subtype Linked to Increased Risk for Severe COVID-19

By

Brandon May

Researchers assessed the risk for severe COVID-19 in patients with microscopic colitis vs the general population.

Anti-Integrin αvβ6 Antibodies Assist in the Diagnosis and Monitoring of Ulcerative Colitis

By

Virginia A. Schad, PharmD, RPh

Investigators assessed whether patients with UC had autoantibodies against integrin αvβ6, a highly specific and sensitive diagnostic biomarker.