Polygenic Risk Score Comprises 12 Variants Capable of Predicting Risk of Cirrhosis
A team of investigators created a polygenic score that could identify a subset of the population at increased risk of developing cirrhosis.
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NEWS
Clinical Tool Helps Optimize Vedolizumab Treatment in Patients With UC
An international team of investigators created a clinical decision support tool to assist in identifying patients with ulcerative colitis most likely to benefit from treatment with vedolizumab.
Use of Direct Acting Antivirals With Potent Inducers Examined in Case Series
While DAAs have improved the treatment of chronic HCV infection by eliciting higher rates of sustained virologic response, they also interact with a number of agents that could potentially limit their effectiveness.
Treatment Success Seen With Antibiotics for Uncomplicated Appendicitis
For adults with uncomplicated acute appendicitis, treatment success rates ≥65 percent are seen with both oral antibiotics and combined intravenous and oral antibiotics.
Evidence Suggests Fecal Transplant Save, Effective for Clostridioides difficile Infections
The FMT National Registry, established by the AGA in partnership with other organizations, provides initial results on the safety and effectiveness of FMT for the management of Clostridioides difficile infections.
Colonic Diverticulitis: A Clinical Practice Update From the AGA
The American Gastroenterological Association provides best practice advice to assist gastroenterologists in making an accurate diagnosis and providing optimal treatment for patients with colonic diverticulitis.
Novel Therapy Fast Tracked for GI Dysfunction in Peds Undergoing Heart Surgery
The designation is based on positive topline data from a phase 2 study of 120 adults following open-heart surgery.
Colorectal Cancer Risk From Obesity Varies by Sex
Higher BMI is associated with a significantly increased risk for colorectal cancer among men, whereas higher waist-to-hip ratio is a strong risk factor among women.
De-Escalate or Discontinue Biologics in IBD?
Although the definition of remission varies, the goal of IBD treatment is to achieve and sustain remission.
Bacterial and Fungal Profiles Estimate Infliximab Response in IBD
A team of investigators sought to determine the influence of infliximab on gut bacterial and fungal composition in patients with inflammatory bowel disease.
The Crohn's Anal Fistula Quality of Life Scale: A Patient-Reported Outcome
As Crohn disease perianal fistulas often do not respond to available treatments, researchers developed a patient-derived quality-of-life tool to evaluate the impact of the condition on patients.
Increased Fecal Proteolytic Activity May Be Potential UC Biomarker
A team of investigators studied a group of asymptomatic patients who were at increased risk of developing inflammatory bowel disease to assess proteolytic activity in advance of a diagnosis of ulcerative colitis.
Despite Diagnosis, Many HCV-Positive Liver Allograft Donors Healthier, Younger
Increased utilization of HCV-positive liver allografts for LT is seen as one of the ways to counter national organ shortages, so researchers set out to better characterize the allografts that come from HCV-positive donors from specific regions.
Combination of FIT and Colonoscopy Boosts Participation in Colorectal Cancer Screening
A team of researchers conducted a multicenter, randomized study to determine the best strategy for offering population-wide screening for colorectal cancer.
Curbing Inherent Bias When Caring for Patients
Bias extends beyond skin color to the assumptions physicians might make about patients.
FDA Authorizes Marketing of EndoRotor System
The U.S. Food and Drug Administration granted marketing authorization to the EndoRotor System, which provides a minimally invasive way to resect and remove necrotic tissue for patients with walled-off pancreatic necrosis.
Real-Time AI-Based Algorithm Successfully Identified Sites During EGD
Given the lack of effective tools available for observing EGD, researchers sought to develop an AI-assisted EGD system to automatically monitor the entire stomach in real time and maintain a record of the procedure time.
Psychological Effects of the COVID-19 Pandemic on Gastroenterologists
The study authors aimed to estimate the prevalence and critical determinants ofpsychological distress among gastroenterologists during the COVID-19 pandemic.
Study Finds Similar Outcomes in Patients With, Without IBD and Rectal Cancer
A team of researchers from the Mayo Clinic aimed to assess survival among patients with rectal cancer with or without inflammatory bowel disease.
Chronic Immune-Mediated Diarrhea and Colitis Associated With Prolonged Survival in Patients Treated With ICIs
The immune-related AE, immune-mediated diarrhea and colitis, can have a limited course or may exist for long-term periods.
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