Researchers aimed to assess the impact of aspirin on incidence of serious GI bleeding in an older population, identify risk factors, and calculate absolute bleeding risk according to age and presence of risk factors.
Investigators assessed the outcomes of patients with peptic ulcer and non-ulcer lesions who did or did not receive pre-endoscopic proton pump inhibitor therapy.
Danish investigators conducted a cohort study to assess the impact of low-dose aspirin on lower gastrointestinal bleeding, colorectal bleeding, and colorectal polyps.
Ticagrelor and prasugrel, the newer generation of P2Y12-inhibiting antiplatelet agents, were found to be associated with fewer gastrointestinal bleeding events the first year after percutaneous coronary intervention compared with clopidogrel.
Researchers conducted a meta-analysis to evaluate prophylactic clipping in preventing post-polypectomy bleeding and published the results in Gastroenterology.
Investigators examined how systemic sclerosis may predict long-term risk for gastrointestinal bleeding, including the bleeding of upper and lower gastrointestinal tracts.
In patients with acute lower gastrointestinal bleeding (ALGIB), colonoscopies performed within 24 hours after hospital admission did not reduce rebleeding or increase stigmata of recent hemorrhage (SRH) compared with colonoscopies performed between 24 to 96 hours after hospital admission.
Patients who restart their blood thinners after a gastrointestinal bleed have a lower risk for dying within the next two years even though they have a higher risk for recurrent gastrointestinal bleeding.
Patients with bleeding gastrointestinal angiodysplasias who are receiving antithrombotic therapy have a lower probability of rebleeding when treated with hemoclips (in combination or as monotherapy), compared with the use of argon plasma photocoagulation.
The incidence of gastrointestinal bleeding was noted in patients taking angiotensin II receptor blockers, and no association was found between proton pump inhibitors and gastrointestinal bleeding.
Resumption of warfarin post-hospitalization for gastrointestinal bleeding (GIB) was associated with an increased risk for recurrent GIB compared with direct oral anticoagulants.
Compared with patients who had gastric gastrointestinal stromal tumors (GISTs), patients with small intestinal GISTs had worse survival and clinical features.
For patients with chronic liver diseases treated with anticoagulant therapy, variceal band ligation is practical due to its lowered incidence of bleeding.
Use of an H2RA may reduce the risk for GI bleeding in high-risk newborns and use of an H2RA or PPI may reduce the duration of upper GI bleeding and incidence of continued bleeding in newborns with this condition.