Both cryoballoon and cryospray ablation therapies are effective in eradicating dysplastic Barrett esophagus.
Coffee, tea, and soda are associated with an increased risk for gastroesophageal reflux symptoms among middle-aged women.
Genomic copy number instability predicted the risk of disease progression among patients with Barrett esophagus years beforehand.
The designation was based on results from Part A of a double-blind, placebo-controlled, pivotal phase 3 trial.
Results of a multicenter, retrospective study of per-oral endoscopic myotomy (POEM) for EGJOO suggest that POEM is an effective and safe therapy.
Patients undergoing sleeve gastrectomy sometimes develop gastroesophageal reflux disease, a major risk factor for Barrett’s esophagus; therefore, researchers investigated whether patients with SG have a high rate of BE.
This phase 3 trial examined whether budesonide orodispersible tablets (0.5 mg or 1 mg, twice daily), with ≤48 weeks of treatment, was superior to placebo in maintaining remission of eosinophilic esophagitis.
Investigators sought to determine whether peroral endoscopic myotomy is safe in patients receiving antithrombotic therapy and examined its clinical success and postprocedural rates of GERD.
A team of investigators assessed the potential for use of proton pump inhibitors to affect the risk of COVID-19 infection.
PPIs are frequently used off-label and are easily accessible as over-the-counter products, contributing to the potential for adverse events or drug-drug interactions.
Adults taking proton pump inhibitors have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship.
Proton pump inhibitors are used inappropriately in approximately 40% of outpatients, indicating limited attention to guidelines.
In a study of kidney transplant recipients, PPI users had an almost 2-fold increased risk of mortality compared with nonusers.
The prevalence of pediatric eosinophilic esophagitis (EoE) may be lower among children living in impoverished areas compared with others.
An international, multicenter study was conducted to assess the long-term safety and efficacy of an experimental monoclonal antibody against interleukin-13 in patients with eosinophilic esophagitis.
Surveillance recommendations are based on the initial grade of dysplasia.
According to the results of tests conducted by the Agency, NDMA levels in ranitidine products can increase over time under normal storage conditions.
A small but significant risk was seen for upper-limb and lower-limb fractures in children who received proton pump inhibitors.
Patients with Barrett’s esophagus undergoing endoscopic eradication therapy demonstrated a low rate of recurrence of intestinal metaplasia and dysplasia after complete eradication of intestinal metaplasia.
An electronic nose that measures volatile organic compounds can detect Barrett esophagus.