Gastroesophageal Reflux Disease (GERD)

Latest News

Tezepelumab Granted Orphan Drug Status for Eosinophilic Esophagitis

By

Brian Park, PharmD

Tezepelumab is a first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin.

Proton Pump Inhibitors, Antiglaucoma Meds Linked to Dry Eye

By

Vincent Soreca

Despite prior suspicion, the review shows no link between dry eye disease and antidepressants or antihypertensives.

Role of Gastroprotective, Promotility Agents in SSc-Interstitial Lung Disease

By

Virginia A. Schad, PharmD, RPh

Do gastroprotective and promotility agents prevent incident interstitial lung disease in patients with systemic sclerosis?

Hypervigilance and Symptom-Specific Anxiety in Patients With Eosinophilic Esophagitis

By

Bradley van Paridon

Investigators assessed the presence and predictive relationship of hypervigilance and symptom-specific anxiety in patients with eosinophilic esophagitis.

Barrett Esophagus: AI System Reliably Quantifies in Real-Time

By

Rita Aghjayan

Investigators evaluated the accuracy of AI assessment of Prague classification and Barrett area quantification from 3D reconstructions of the esophageal surface from 2D endoscopic imaging.

A Case of Sudden-Onset Dysphagia During Lunch, Unresolved by PPIs

By

Karmen Elsen, MPA, PA-C

A patient presenting with sudden-onset dysphagia and vomiting initially is diagnosed with GERD but does not respond to PPIs. What is your diagnosis?

Factors Contributing to Carbapenemase-Producing Carbapenem-Resistant Enterobacterales

By

Bradley van Paridon

Researchers compared different factors among US veterans with and without carbapenemase-producing carbapenem-resistant Enterobacterales cultures.

Optimal Age to Stop Surveillance of Patients With NDBE Dependent on Sex and General Health

By

Colby Stong

Investigators aimed to determine the ideal age to discontinue surveillance in patients with non-dysplastic Barrett esophagus based on sex and comorbidities.

Hill Grade on EGD Is Associated With GER in Children and Adolescents

By

Colby Stong

Investigators sought to evaluate the relationship between Hill grade confirmed with EGD and the degree of gastroesophageal reflux in children with GERD.

Etrasimod Granted Orphan Drug Status for Eosinophilic Esophagitis

By

Brian Park, PharmD

Etrasimod is an investigational, next generation, once-daily, oral, highly selective sphingosine 1-phosphate receptor modulator.

Dysphagia Prevalence, Characteristics Among Patients With Obstructive Sleep Apnea

By

Sheila Jacobs

Approximately one-sixth of patients with obstructive sleep apnea (OSA) have demonstrated symptoms of dysphagia.

Refractory GERD Reduced With STRETTA in Patients With Prior Gastric Surgery

By

Rita Aghjayan

Investigators reviewed the outcomes of STRETTA in patients with refractory GERD who underwent prior gastric surgery.

Short Meal-to-Bed Time Associated With GERD in Women Who Are Pregnant

By

Brandon May

Investigators assessed the characteristics of GERD and the relationship between meal-to-bed-time and GERD during pregnancy.

Radiofrequency Ablation with Endoscopic Resection Effective, Durable Treatment for Barrett Esophagus

By

Emily Pond

Investigators examined short-term and long-term outcomes of patients treated for BE with dysplasia and/or early cancer, according to a uniform protocol.

Radiofrequency Ablation Modestly Reduces Low-Grade Dysplasia in Barrett Esophagus

By

Virginia A. Schad, PharmD, RPh

Researchers aimed to confirm the results of two previous RCTs comparing the effectiveness of radiofrequency ablation vs surveillance in patients with Barrett Oesophagus.

Unexplained Gastrointestinal Disorders Remain Relatively Stable in a Specific Population Over 20 Years

By

Jessica Nye, PhD

Researchers analyzed the trends and prevalence of chronic, unexplained GI symptoms in a single community over a 20 year span.

Superior Symptom Control and Quality of Life with Surgery vs Medical Treatment of GERD

By

Virginia A. Schad, PharmD, RPh

Researchers performed a systematic review and meta-analysis to compare different medical and surgical interventions in the treatment of GERD.

Obstructive Sleep Apnea Syndrome May Reduce Hypopharyngeal Reflux Events in Laryngopharyngeal Reflux

By

Vincent Soreca

A team of investigators conducted a prospective study to explore the profile of patients with OSAS and LPR at the HEMII-pH and to compare the reflux findings with LPR patients without OSAS.

pH Meter and pH Paper May Be Useful for Monitoring Tube-Fed Children With Neurologic Impairment and GERD

By

Colby Stong

Investigators analyzed the agreement among pH paper, hand-held pH meters, and laboratory pH meters for gastric pH measurements in tube-fed children with neurological impairments and GERD.

Surgical Intervention for Acid-Reflux Control More Efficacious and Cost-Effective Than Long-Term PPI Use

By

Jessica Nye, PhD

Researchers assessed the efficacy and cost-effectiveness of proton pump inhibitors vs surgical intervention for acid reflux control.