Gastric Malignancies

Latest Articles

Obesity Tied to Increased Mortality Overall in Patients With Cancer

For patients with cancer, obesity is associated with worse overall and cancer-specific mortality.

Targeting WNT2 Secreted by CAFs May Improve Antitumor T-Cell Response

By

Emily Pond

Investigators explored the mechanism by which solid tumors appear to resist immune checkpoint inhibitor therapies.

Performance of Endoscopists Associated With 10-Year CRC Risk

By

Jessica Nye, PhD

Researchers analyzed the impact of colonoscopists’ performance on colorectal cancer risk following adenoma removal.

Outcomes for Complex GI Cancer Surgery Better at Top-Ranked Hospitals

For patients who require complex gastrointestinal cancer surgery, outcomes are improved when surgery is performed at top-ranked hospitals.

CADe Software Accurate for Colorectal Polyp Detection

By

Colby Stong

A new CADe software for colorectal polyp detection was validated and compared against a composite reference standard of experienced endoscopists and CADe detection.

Effect of Antithrombotic Drugs on FIT for CN Detection

By

Brandon May

Investigators examined the effects of antithrombotic drugs on fecal immunochemical tests (FITs) for detection of colorectal neoplasms (CN).

H pylori Infection and Early GC

By

Virginia A. Schad, PharmD, RPh

Researchers assessed the correlation between Helicobacter pylori infection and biological characteristics of early gastric cancer.

BMI Linked to Vonoprazan Effectiveness as Second-Line Helicobacter pylori Treatment

By

Colby Stong

A team of investigators sought to determine factors that affect the success of second-line therapy using vonoprazan, a gastric acid secretion inhibitor that improves the success rate of Helicobacter pylori eradication.

IT Knife Tunneling Esophageal ESD: Introducing a Japanese Technique

By

Vincent Soreca

A team of investigators conducted a prospective, single-center, observational study at the Cleveland Clinic to determine the safety and feasibility of IT-knife tunneling and C-shaped incision endoscopic submucosal dissection of the esophagus.

ASCO Publishes 2021 Report on Progress Against Cancer

By

Andrea S. Blevins Primeau, PhD, MBA

The American Society of Clinical Oncology (ASCO) highlights the past year’s oncologic advances and identifies important areas for future research in its 2021.

GERD Linked to Squamous Cell Cancers of Larynx, Esophagus

Gastroesophageal reflux disease appears to be associated with an increased risk for squamous cell cancers of the larynx and esophagus.

Contrast-Enhanced vs Conventional Endoscopic Ultrasound for Pancreatic Lesion Diagnosis

By

Brandon May

A team of investigators sought to investigate the usefulness of contrast-enhanced harmonic ultrasound-guided fine needle aspiration/biopsy when performed with no on-site cytopathology.

High Social Vulnerability and Poorer Outcomes Following Cancer Surgery

By

Vincent Soreca

Investigators sought to determine the effect of community-level factors on surgical outcomes, paying particular attention to differences in “textbook outcome” relative to social vulnerability among Medicare beneficiaries who underwent surgery for cancer.

Impact of Circulating Sex Hormones on Risk of Gastrointestinal Cancer

By

Brandon May

A team of investigators sought to determine the relationship between circulating sex hormones and risk of esophageal, gastric, and colorectal cancers in both men and women.

AI Tool Shows Promise for Predicting Gastric Cancer Risk After Helicobacter Pylori Eradication

By

Vincent Soreca

A team of investigators explored the ability of different machine learning models to predict the risk of gastric cancer development in patients who had undergone eradication of Helicobacter pylori infection.

OS Benefit Modest or Absent With Many High-Cost Therapies Approved for GI Malignancies

By

Victoria Forster, PhD

Investigators assessed disparities in patient access to therapies approved for the treatment of gastrointestinal malignancies in the United States, the United Kingdom, Europe, and Ireland, as well as benefit relative to cost.

PERT Shows Promise in Unresected Pancreatic Cancer

By

Colby Stong

Investigators compared the outcomes of patients who received pancreatic enzyme replacement therapy (PERT) with those who did not.

Opioid Use May Contribute to Risk for Pancreatic Cancer

At the state level, opioid death rate at four years prior predicted the initial incidence of pancreatic cancer.

Assessment of Self-Expandable Metallic Stents in Malignant Distal Biliary Strictures

By

Virginia A. Schad, PharmD, RPh

Researchers assessed the efficacy and adverse outcomes with plastic stents vs self-expandable metallic stents for the management of malignant distal biliary strictures.

Zanidatamab Active in HER2-Positive Biliary Tract Cancer

By

Leah Lawrence

Bernstam et al presented findings from an expansion cohort of a phase 1 trial testing the bispecific HER2-targeted antibody zanidatamab in patients with HER2-overexpressing biliary tract cancer.