In this study, there was no correlation between the presence of MET gene amplification and the presence of MET protein overexpression.
The researchers recommend that [endoscopic ultrasound-guided gallbladder drainage] be used as one of the first-line approaches when treating this patient population and is preferably performed in centers with high expertise owing to the chances of rare but serious adverse events.
Acute pancreatitis should be high on the differential diagnosis list when evaluating abdominal symptoms in adolescents who undergo laparoscopic sleeve gastrectomy.
The FDA has cleared the first duodenoscope with a disposable sterile elevator piece, a first in the United States. The design will reduce the number of parts that need to be cleaned and disinfected (reprocessed) between uses.
Delaying cholecystectomy for acute cholecystitis for more than 72 hours after admission is associated with an increased length of stay and increased rates of complications and readmission.
Study investigators concluded that although the optimum treatment course for common bile duct stones has not yet been determined, “ERCP for CBD stone clearance involves multiple interventions, prolonged treatment, causes post procedure morbidity and high treatment costs.
The involvement of the biliary tract in bacteremia caused by Staphylococcus aureus may be more likely to develop in certain patients and aggressive treatment should be considered.
Individuals with genetic variants linked to increased coffee consumption have reduced risk for gallstones.
Nearly half of patients with early-stage PBC progress to a more severe stage within 5 years. Progression is associated with increased risk of a clinical event, so surveillance is important for patients with early-stage PBC.
Researchers conducted a retrospective cohort study to determine the clinical features of pediatric patients with PSC in a Japanese cohort to evaluate long-term outcomes. They discovered that primary sclerosing cholangitis (PSC)-autoimmune hepatitis overlap is the primary phenotype linked to poor long-term outcomes.
The researchers observed an increased risk for acute gallbladder or biliary disease with liraglutide versus placebo (hazard ratio, 1.60). Similar findings were seen for each of the four categories of gallbladder- or biliary tract-related events (uncomplicated gallbladder stones, complicated gallbladder stones, cholecystitis with/without gallbladder stones, and biliary obstruction).
No significant differences in surgical complication risk were seen in early or delayed cholecystectomy for acute cholangitis and acute cholecystitis.
At a routine follow-up visit at the clinic a month prior, the patient reported consuming at least 2 bags of unpeeled lemons per day.