Researchers identified abdominal pain, low serum carbohydrate antigen (CA) 19.9 levels, and absence of mass on imaging as independent predictors of benign lesions in patients with proximal biliary strictures (PBS), as indicated by study data published in HPB. According to the researchers, the aforementioned risk factors may be used to differentiate benign lesions from perihilar…
When diagnosing indeterminate biliary strictures, digital single-operator cholangioscopy (DSOC)-guided biopsy has demonstrated safety, efficacy, and higher sensitivity than standard endoscopic retrograde cholangiopancreatography.
The researchers recommend that [endoscopic ultrasound-guided gallbladder drainage] be used as one of the first-line approaches when treating this patient population and is preferably performed in centers with high expertise owing to the chances of rare but serious adverse events.
The FDA has cleared the first duodenoscope with a disposable sterile elevator piece, a first in the United States. The design will reduce the number of parts that need to be cleaned and disinfected (reprocessed) between uses.
Study investigators concluded that although the optimum treatment course for common bile duct stones has not yet been determined, “ERCP for CBD stone clearance involves multiple interventions, prolonged treatment, causes post procedure morbidity and high treatment costs.
Nearly half of patients with early-stage PBC progress to a more severe stage within 5 years. Progression is associated with increased risk of a clinical event, so surveillance is important for patients with early-stage PBC.
Researchers conducted a retrospective cohort study to determine the clinical features of pediatric patients with PSC in a Japanese cohort to evaluate long-term outcomes. They discovered that primary sclerosing cholangitis (PSC)-autoimmune hepatitis overlap is the primary phenotype linked to poor long-term outcomes.
The researchers observed an increased risk for acute gallbladder or biliary disease with liraglutide versus placebo (hazard ratio, 1.60). Similar findings were seen for each of the four categories of gallbladder- or biliary tract-related events (uncomplicated gallbladder stones, complicated gallbladder stones, cholecystitis with/without gallbladder stones, and biliary obstruction).