Tezepelumab is a first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin.
The addition of nivolumab to chemotherapy demonstrated continuing improved survival compared with chemotherapy alone after 24 months of follow-up.
The application is supported by data from the phase 3 RATIONALE 302 trial.
Investigators sought to develop and validate a risk prediction model for death within 90 days after esophagectomy for cancer, utilizing the IESG database
Investigators assessed the presence and predictive relationship of hypervigilance and symptom-specific anxiety in patients with eosinophilic esophagitis.
Investigators assessed the cardiac-specific mortality rate among patients with major GI cancers, as well as the relationship between radiation and chemotherapy with survival outcomes.
Investigators evaluated the accuracy of AI assessment of Prague classification and Barrett area quantification from 3D reconstructions of the esophageal surface from 2D endoscopic imaging.
Investigators compared the efficacy of neoadjuvant chemoradiotherapy plus surgery vs surgery alone for treatment of advanced esophageal squamous cell carcinoma.
A patient presenting with sudden-onset dysphagia and vomiting initially is diagnosed with GERD but does not respond to PPIs. What is your diagnosis?
Investigators compared outcomes of intrathoracic vs cervical anastomosis following transthoracic minimally invasive esophagectomy.
Investigators aimed to determine optimal chemotherapy dosing for older, frail patients with gastroesophageal cancer and use of geriatric assessment as a decision making tool.
Investigators aimed to determine the ideal age to discontinue surveillance in patients with non-dysplastic Barrett esophagus based on sex and comorbidities.
Investigators sought to evaluate the relationship between Hill grade confirmed with EGD and the degree of gastroesophageal reflux in children with GERD.
Researchers investigated whether varicella zoster virus is linked to achalasia.
Researchers reviewed the current status of and advances in the detection of Barrett esophagus and risks for esophageal adenocarcinoma.
Etrasimod is an investigational, next generation, once-daily, oral, highly selective sphingosine 1-phosphate receptor modulator.
The approval was based on data from the phase 3 CheckMate-577 trial which included 794 adults with completely resected esophageal or GEJ cancer who had residual pathologic disease following neoadjuvant CRT.
Approximately one-sixth of patients with obstructive sleep apnea (OSA) have demonstrated symptoms of dysphagia.
The accelerated approval was based on data from the KEYNOTE-811 study.
Investigators examined short-term and long-term outcomes of patients treated for BE with dysplasia and/or early cancer, according to a uniform protocol.