Esophagus

Latest Articles

Intrathoracic vs Cervical Anastomosis Following Transthoracic MIE for Esophageal Cancer

By

Vincent Soreca

Investigators compared outcomes of intrathoracic vs cervical anastomosis following transthoracic minimally invasive esophagectomy.

Reduced-Intensity Chemotherapy in Older, Frail Patients With Gastroesophageal Cancer

By

Rita Aghjayan

Investigators aimed to determine optimal chemotherapy dosing for older, frail patients with gastroesophageal cancer and use of geriatric assessment as a decision making tool.

Optimal Age to Stop Surveillance of Patients With NDBE Dependent on Sex and General Health

By

Colby Stong

Investigators aimed to determine the ideal age to discontinue surveillance in patients with non-dysplastic Barrett esophagus based on sex and comorbidities.

Hill Grade on EGD Is Associated With GER in Children and Adolescents

By

Colby Stong

Investigators sought to evaluate the relationship between Hill grade confirmed with EGD and the degree of gastroesophageal reflux in children with GERD.

Achalasia May Be Associated With Salivary VZV DNA

By

Colby Stong

Researchers investigated whether varicella zoster virus is linked to achalasia.

Nonendoscopic Detection for Barrett Esophagus May Also Identify Esophageal Adenocarcinoma

By

Rita Aghjayan

Researchers reviewed the current status of and advances in the detection of Barrett esophagus and risks for esophageal adenocarcinoma.

Etrasimod Granted Orphan Drug Status for Eosinophilic Esophagitis

By

Brian Park, PharmD

Etrasimod is an investigational, next generation, once-daily, oral, highly selective sphingosine 1-phosphate receptor modulator.

Opdivo Approved as Adjuvant Treatment for Completely Resected Esophageal, GEJ Cancer

By

Brian Park, PharmD

The approval was based on data from the phase 3 CheckMate-577 trial which included 794 adults with completely resected esophageal or GEJ cancer who had residual pathologic disease following neoadjuvant CRT.

Dysphagia Prevalence, Characteristics Among Patients With OSA

By

Sheila Jacobs

Approximately one-sixth of patients with obstructive sleep apnea (OSA) have demonstrated symptoms of dysphagia.

Keytruda Combo Approved for First-Line Treatment of HER2-Positive Gastric Cancer

By

Diana Ernst, RPh

The accelerated approval was based on data from the KEYNOTE-811 study.

RFA with ER Effective, Durable Treatment for BE

By

Emily Pond

Investigators examined short-term and long-term outcomes of patients treated for BE with dysplasia and/or early cancer, according to a uniform protocol.

LCI for Polyp Detection, Adenomas in Lynch Syndrome

By

Emily Pond

Investigators compared the use of linked color imaging vs high-definition white light endoscopy for detection of polyps in patients with Lynch syndrome.

Adjuvant Nivolumab in Esophageal and GEJ Cancers

By

Andrea S. Blevins Primeau, PhD, MBA

Residual pathologic disease often remains after neoadjuvant chemotherapy and resection in patients with esophageal or GEJ cancers, and these patients have a high risk of recurrence.

Opdivo Plus Chemotherapy Approved for Treatment of Gastric Cancer

Opdivo (nivolumab) is now approved for the treatment of advanced or metastatic gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma.

Opdivo Plus Chemotherapy Approved for First-Line Treatment of Gastric Cancer

By

Brian Park, PharmD

Opdivo is a programmed death receptor-1 (PD-1)-blocking antibody.

nCRT With MIE vs nCT With MIE for ESCC

By

Colby Stong

Researchers compared safety and long-term survival of nCRT followed by MIE vs nCT followed by MIE in patients with advanced ESCC.

RFA Modestly Reduces LGD in Barrett Esophagus

By

Virginia A. Schad, PharmD, RPh

Researchers aimed to confirm the results of two previous RCTs comparing the effectiveness of radiofrequency ablation vs surveillance in patients with Barrett Oesophagus.

Disinfection With PAA May Reduce Risk of SARS-CoV-2 Spread Following Endoscopy

By

Brandon May

Investigators examined the effectiveness of the PARP inhibitor olaparib in patients with pancreatic cancer with BRCAness.

tSVFem Delivery for Treatment of Upper GI Lesions

By

Jessica Nye, PhD

Researchers presented a case series for the use of endoscopic delivery of stromal vascular fraction obtained by mechanical emulsification of autologous adipose tissue in patients with upper GI tract fistulas.

Targeting WNT2 Secreted by CAFs May Improve Antitumor T-Cell Response

By

Emily Pond

Investigators explored the mechanism by which solid tumors appear to resist immune checkpoint inhibitor therapies.