Crohn Disease

Latest Articles

Anxiety and Depression Common in Patients With Inflammatory Bowel Disease

By

Colby Stong

Researchers assessed the prevalence of symptoms of anxiety and depression in adult patients with irritable bowel disease.

Current Treatments for Patients With Inflammatory Bowel Diseases Experiencing Extraintestinal Manifestations

By

Jessica Nye, PhD

Researchers summarized the current knowledge on treatment options for extraintestinal manifestations in patients with IBD, while calling attention to gaps in the research.

Opioids and IBD: Current Challenges

By

C. Andrew Kistler, MD, PharmD

Initiation of opioid use during a flare of symptoms can eventually lead to chronic opioid use (COU), which can have detrimental effects on a patient’s IBD, as well as their overall clinical health.

Depression and Gastrointestinal Symptoms Linked to Inflammatory Bowel Disease

By

Vincent Soreca

Researchers investigated whether psychological comorbidities predated the diagnosis and propagation of inflammatory bowel disease.

Pediatric Crohn Disease Linked to Low Bone Mineral Density

By

Vincent Soreca

Researchers examined the effects of nutritional therapy on bone health in pediatric patients with Crohn Disease.

Laparoscopic Strictureplasty: A Safe, Feasible Treatment for Complicated Crohn Disease

By

Emily Pond

Investigators sought to determine the safety and feasibility of conventional and non-conventional laparoscopic strictureplasties for the treatment of Crohn Disease.

Overview of Crohn Disease Management Following Gastrointestinal Cancer Onset

By

Vincent Soreca

Reviewers provided an overview of evidence for appropriate diagnostic pathway and management of Crohn disease following GI cancer onset.

Influence of PPI Therapy on Outcome of Infliximab Therapy in IBD

By

Virginia A. Schad, PharmD, RPh

A team of investigators sought to determine how concomitant proton pump inhibitor treatment influences response to infliximab therapy in patients with inflammatory bowel disease.

Low Health Literacy Among IBD Population More Common in Older Black Persons

By

Vincent Soreca

A team of investigators evaluated the prevalence of and sought to identify risk factors associated with low health literacy in a diverse population of individuals with inflammatory bowel disease.

Kidney Function Monitoring Strategy to Prevent 5-Aminosalicylic Acid Nephrotoxicity in IBD

By

Vincent Soreca

Investigators performed a literature review of current strategies for monitoring kidney function in patients undergoing treatment with 5-ASA for inflammatory bowel disease.

Crohn Disease, Comorbidities Increase Risk for Severe Pneumococcal Disease

For veterans with inflammatory bowel disease, the risk for severe pneumococcal disease is increased with Crohn disease and with more comorbidities, and pneumococcal vaccination is associated with a reduced risk for SPD.

Study Finds Link Between Depression, Anxiety Symptoms and Disease Activity in IBD

By

Vincent Soreca

A team of investigators examined the association between disease activity in individuals with inflammatory bowel disease and the development of symptoms of depression and anxiety.

Study Shows Infliximab Superior to Traditional Therapy in Youth With Crohn Disease

By

Vincent Soreca

More research and follow-up on infliximab is needed to determine the appropriate length of treatment and who will benefit most from treatment.

Stoma Formation in Crohn Disease Associated With Antidepressant Use

By

Virginia A. Schad, PharmD, RPh

A team of investigators conducted a nationally representative, population-based cohort study to assess the use of antidepressant medication in patients having undergone surgery for Crohn disease.

De-Escalation and Discontinuation of Biologics in IBD: What to Consider

By

C. Andrew Kistler, MD, PharmD

Although the definition of remission varies, the goal of IBD treatment is to achieve and sustain remission.

Bacterial and Fungal Profiles Estimate Infliximab Response in Patients With IBD

By

Virginia A. Schad, PharmD, RPh

A team of investigators sought to determine the influence of infliximab on gut bacterial and fungal composition in patients with inflammatory bowel disease.

The Crohn’s Anal Fistula Quality of Life Scale: A Patient-Reported Outcome Measure

By

Virginia A. Schad, PharmD, RPh

As Crohn disease perianal fistulas often do not respond to available treatments, researchers developed a patient-derived quality-of-life tool to evaluate the impact of the condition on patients.

Clinical Remission Observed With Risankizumab in Crohn Disease Trials

By

Brian Park, PharmD

Risankizumab is currently FDA-approved under the brand name Skyrizi for the treatment of moderate to severe plaque psoriasis.

Improved Psychological Support Is Needed After Stoma Surgery

By

Jessica Nye, PhD

Interview study identified categories in which improved psychological support services are needed for these patients.

Socioeconomic Status Influences Inflammatory Bowel Disease Outcomes

Lower socioeconomic status is associated with worse outcomes for inflammatory bowel disease.