Crohn Disease

Latest Articles

Prevalence of Depression in Inflammatory Bowel Disease

By

Rita Aghjayan

Researchers assessed whether depression in the presence or absence of previous GI symptoms is associated with a future diagnosis of IBD.

Regular Use of Proton Pump Inhibitors May Increase Risk for Inflammatory Bowel Diseases

By

Jessica Nye, PhD

Investigators evaluated the association between regular proton pump inhibitor use and the risk for inflammatory bowel disease and its subtypes.

Ultra-Processed Foods Associated With Risk for Crohn Disease

By

Emily Pond

Investigators analyzed the association between consumption of ultra-processed foods and risk for Crohn disease and ulcerative colitis.

Unclear Evidence On Abdominal Pain Management Among Patients With Ulcerative Colitis

By

Jessica Nye, PhD

Authors assessed the safety and efficacy of current methods for managing abdominal pain in patients with ulcerative colitis.

AbbVie Seeks Approval of Risankizumab for Crohn Disease

By

Brian Park, PharmD

The application is supported by data from two phase 3 induction studies (ADVANCE and MOTIVATE) and one phase 3 maintenance study (FORTIFY).

Prevalence of Primary Sclerosing Cholangitis in IBD Examined

The global prevalence of primary sclerosing cholangitis ranges from 0.96 percent in Crohn disease to 2.47 percent in ulcerative colitis.

Host Antibody Response to Microbial Antigens May Be Early Marker of Crohn Disease

By

Emily Pond

Investigators assessed whether increased antibody responses to microbial antigens is an independent risk factor for future development of Crohn disease.

Dietary Patterns Influence Structure, Function of Gut Microbiome in IBD

By

Rita Aghjayan

Researchers described the evolution of dietary patterns and the outcomes they have on the gut microbiome, immune function, and inflammation in people with IBD.

IBD and Obesity: Is There a Connection?

By

C. Andrew Kistler, MD, PharmD

One key factor that has developed increasing research interest is the role of a patient’s BMI, specifically those with obesity (BMI > 30 kg/m2), in the development of IBD.

Inflammatory Bowel Disease: Extraintestinal Manifestations

By

Jennifer Champagne, PharmD, RPh, BCPS

Investigators reviewed the current clinical presentations and treatment options for extraintestinal manifestations in patients with inflammatory bowel disease.

Pediatric Gastroenterologists Prefer Initial Withdrawal of Immunomodulator in Step-Down Process in PIBD

By

Colby Stong

Researchers assessed the practices favored by pediatric gastroenterologists for combination immunosuppression in patients with pediatric inflammatory bowel disease.

Safety, Efficacy of COVID-19 Vaccine in IBD

By

Rita Aghjayan

Investigators performed a retrospective analysis to compare COVID-19 vaccine outcomes in patients with IBD against those without.

Corticosteroid Use Declines in Patients With IBD Over Past 20 Years

By

Colby Stong

Investigators assessed trends in corticosteroid use in patients with IBD over a period of 20 years.

IBD Risk Not Linked to Empirical Dietary Inflammatory Pattern Score

By

Colby Stong

Researchers evaluated whether higher empirical dietary inflammatory pattern scores were associated with increased risk of developing IBD.

The Role of Interleukin-2-Inducible T-cell Kinase in Ulcerative Colitis

By

Jennifer Champagne, PharmD, RPh, BCPS

Investigators attempted to define the role of interleukin-2-inducible T-cell kinase activation in ulcerative colitis.

Risankizumab Safe, Effective for Long-Term Treatment of Crohn Disease

By

Emily Pond

Investigators conducted an open-label extension to evaluate the long-term safety and efficacy of risankizumab for the treatment of moderate to severe Crohn disease.

Validation of Lémann Index Assessing Bowel Damage in Patients With Crohn Disease

By

Bradley van Paridon

Investigators aimed to evaluate and update the Lémann index for the assessment of cumulative bowel damage in patients with Crohn disease.

Microscopic Colitis: Is Vedolizumab An Option?

By

C. Andrew Kistler, MD, PharmD

Due to the relatively high relapse rate and need for additional therapies, current research is being done on the use of Vedolizumab for the treatment of microscopic colitis.

Studies Support Transmural Healing as a Relevant Treatment Target in Crohn Disease

By

Brandon May

Investigators performed a systematic review to examine the varying definitions of transmural healing and assess its impact on CD-related outcomes.

Specific Carbohydrate Diet and Mediterranean Diet Lead to Similar Symptom Remission in Crohn Disease

By

Brandon May

Researchers compared the effectiveness of the specific carbohydrate diet with the Mediterranean diet for the management of Crohn disease symptoms.