Molecular Evidence Suggests Similar Treatment Targets for IBD or COVID-19
Therapies for the treatment of inflammatory bowel disease may have a potential use in patients with COVID-19.
Crohn Disease
CROHN DISEASE
Latest Articles
Vedolizumab Is Safe Long-Term for Ulcerative Colitis and Crohn Disease
Alimentary Pharmacology and Therapeutics reports on the final results from the GEMINI long-term safety study on vedolizumab, a gut-selective α4 β7 integrin antibody approved for moderately to severely active ulcerative colitis and Crohn disease.
Pro-Inflammatory Diets May Increase Risk for Crohn Disease
An analysis of 3 large prospective cohorts examined the association between dietary patterns with high inflammatory potential and increased risks for Crohn disease and ulcerative colitis.
Crohn Disease: Steroid IV Therapy Boosts Risk for Short Bowel Syndrome
Researchers analyzed independent risk factors for short bowel syndrome in patients with Crohn disease in an effort to develop preventive strategies.
Inflammatory Bowel Disease and the Risk of Extraintestinal Cancers
A team of investigators conducted a systematic review and meta-analysis to assess the risk of extraintestinal cancer in patients with inflammatory bowel disease.
IBDDI More Reliably Measures IBD-Related Disability Among Different Cultures Than Generic Tools
Researchers compared the predictive properties of the IBDDI from among 5populations of individuals living with IBD, most of whom had Crohn disease as well.
Cannabis May Improve Quality of Life for IBD Patients
Although cannabis use does not induce clinical remission in IBD, patient-reported quality of life may improve.
Crohn Disease Recurrence Associated With Positive Resection Margins, Other Risk Factors
Positive resection margins, granulomas, and myenteric plexitis are all predictive of postoperative Crohn disease recurrence.
IBD-F Assessment Scale Predicts Fatigue Level and Shows Negative QoL in IBD
A longitudinal cohort study was conducted to validate the IBD-F scale in the assessment of clinically significant fatigue, as well as to identify the impact of fatigue on quality of life in patients with IBD.
Genetic Predictors May Determine Treatment Response in Pediatric Inflammatory Bowel Disease
This is the first study to report polymorphisms associated with long term response to anti-TNF treatment in pediatric patients with Crohn disease and ulcerative colitis.
Increased Intestinal Permeability May be Associated With Crohn Disease
Increased intestinal permeability may be associated with the development of Crohn disease.
ASCRS Updates Guidelines on Surgery for Crohn Disease
The researchers note that surgery should typically be considered for patients who demonstrate an inadequate response to, develop complications from, or are nonadherent with medical therapy.
Ortikos Now Available for Mild to Moderate Crohn Disease
Ortikos, an anti-inflammatory corticosteroid, is approved as a once-daily treatment for mild to moderate active Crohn disease and for maintenance of clinical remission.
Inflammatory Bowel Disease Associated With Higher Bacterial, Viral Meningitis Risk
Study finds that patients with IBD and 1 or more comorbidities are at increased risk for viral or bacterial meningitis.
Efficacy of Cannabinoids in Treating IBD Examined
Significant improvements in both clinical symptoms (ie, abdominal pain, general well-being, nausea, diarrhea, and decreased appetite) as well as QoL scores were observed with cannabinoids.
Automated Ulcer Severity Grading Model Accurate in Crohn Disease
A team of investigators assessed the accuracy of a machine learning model in grading the severity of ulcers in patients with Crohn disease.
Psoriasis, Psoriatic Arthritis Associated With Inflammatory Bowel Disease and Other Gastrointestinal Illnesses
Researchers evaluated the association of psoriasis and psoriatic arthritis with inflammatory bowel disease and other gastrointestinal illnesses.
Guideline Issued on the Use of Probiotics for Managing GI Disorders
Probiotics should only be recommended for specific patient populations since there is not enough evidence to support their use in the majority of digestive conditions, according to new clinical guidelines released by the American Gastroenterological Association (AGA) and recently published in Gastroenterology.
Perianal Fistulizing Complications Preventable in Crohn Disease
Steroid-sparing therapy may reduce risk for PFCs in young patients with Crohn disease
Fecal Calprotectin Level After Bowel Resection is Predictive of Endoscopic Postoperative Recurrence in Crohn Disease
Variation in fecal calprotectin levels after ileocolonic resection is an accurate predictor of early endoscopic POR in patients with Crohn’s disease.
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