The study reaffirms that pathology should be questioned as the gold standard for diagnosing colorectal lesions ≤ 3mm; especially, when high confidence optical evaluation identifies an adenoma. It is therefore imperative that all endoscopists incorporate optical evaluation, coupled with high-quality photo documentation, into clinical practice.
Until the healthcare industry can more adequately handle big data, adapt to artificial intelligence, and gather more evidence surrounding the efficacy of precision medicine for CRC, healthcare providers and patients must remain aware of hype, while also remaining optimistic about the hope of the individualized treatment and prevention of CRC.
Implementation of the Dependent Coverage Expansion under the ACA increased early-stage colorectal cancer diagnosis and receipt of timely adjuvant chemotherapy for surgically resected stage IIB to IIIC CRC among DCE-eligible patients.
Following publication of updated guidelines by the American Cancer Society recommending that the age for colorectal cancer screening be lowered to 45 years, there was an increase in screening among those aged 45 to 49 years.
Researchers find that high-definition white-light endoscopy, performed by experienced and dedicated endoscopists, may be an acceptable alternative to pancolonic chromoendoscopy for the detection of adenomas in patients under surveillance for Lynch syndrome.
Overall, the researchers discovered thatω-3 supplementation of 1 g per day was not associated with risk of a colorectal premalignant lesion. However, the findings did not rule out a potential benefit of marine ω-3 fatty acid either at higher doses or in high-risk populations, as reported in previous studies of patients with familial adenomatous polyposis14 or with established CRC.
The rate of CRC after diverticulitis is significantly higher than the rate observed at screening colonoscopy, regardless of whether the disease is complicated, and that colonoscopy should be performed following diverticulitis diagnosis.
The study researchers concluded that clopidogrel has a protective effect on CRC comparable to that of low-dose aspirin, which contributes to the concept that platelet targeting may be a promising strategy for disease prevention.
In patients with inflammatory bowel diseases (IBD) who underwent colonoscopic surveillance for colorectal neoplasia (CRN), indefinite dysplasia was independently associated with a significant increase in advanced CRN risk.
Gastroenterology Advisor spoke to Dr. Robert McLean, President of the American College of Physicians (ACP), and Dr. Timothy Wilt, Chair of ACP’s Clinical Guidelines Committee to address several of these questions from the Colorectal Cancer Screening Guidance Statement.