The FDA has approved Keytruda (pembrolizumab; Merck), a programmed death receptor-1 -blocking antibody, as monotherapy for the first-line treatment of patients with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
People with first-degree relatives who have colorectal cancer (CRC) are at increased risk for the development of colorectal neoplasia and should be screened for the disease early and frequently.
The gut microbiome has become one of the most researched topics in gastroenterology. However, it is not yet understood how changes to the gut microbiome affect certain malignancies, particularly colorectal cancer (CRC). Despite improvements in detection and prevention by colonoscopy and other forms of testing, CRC still has a significant effect on patient morbidity and…
Patients with stage III and IV cancer have worse quality of life during the COVID-19 pandemic.
Linked-color imaging outperformed white-light colonoscopy in the detection of colon adenomas, according to cohort study.
Patients with high-risk adenomas (HRAs) detected during colonoscopy should undergo an additional surveillance procedure even if intervening negative results are present,
Patients treated with non-vitamin K antagonist oral anticoagulants (NOACs) following atrial fibrillation were more likely to develop gastrointestinal bleeding and malignancies.
For patients with Lynch syndrome, aspirin is associated with a reduced risk for colorectal cancer during long-term follow-up.
Study data support the use of quantitative fecal immunochemical tests (FITs) for the detection of colorectal cancer (CRC) and advanced adenomas.
The guideline includes four recommendations for individuals, the first of which is achieving and maintaining a healthy body weight throughout life and avoiding weight gain in adult life.
Researchers conducted a meta-analysis to evaluate prophylactic clipping in preventing post-polypectomy bleeding and published the results in Gastroenterology.
The involvement of gastroenterology fellows in the administration of colonoscopy procedures may improve adenoma detection rate.
Modest delays in cancer surgery due to the COVID-19 pandemic could have a significant impact on survival.
The COVID-19 pandemic has caused a substantial decrease in endoscopy services in Hong Kong, which has been led to significant delays in the diagnosis of GI cancers.
In response to the COVID-19 pandemic, a number of North American gastroenterology institutions have implemented changes to clinical practice.
Colorectal polyps that are 1-20 mm in size are frequently resected incompletely, according to recent study data.
The total lifetime risk for colorectal cancer (CRC) in patients with ulcerative colitis (UC) was comparable to that observed in the general population.
Endoscopic surveillance was safe and effective in a prospective cohort of patients with serrated polyposis syndrome (SPS) and over 10 years of follow-ups.
Higher body mass index (BMI) is associated with increased risk of colorectal cancer, more so for men than for women.
Patients with proximal 5 to 9 mm hyperplastic polyps (HPs) are at significantly elevated risk for metachronous large serrated polyps (SPs).