Bylvay Approved for Progressive Familial Intrahepatic Cholestasis
Bylvay is an oral reversible inhibitor of the ileal bile acid transporter.
Chronic Liver Disease
CHRONIC LIVER DISEASE
Latest News
Better Strategies Needed for Managing NAFLD in Adults
Effective screening, diagnosis, and management strategies are needed for patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Lenvatinib Beneficial for Health-Related Quality of Life in Unresectable Hepatocellular Carcinoma
In a post-hoc analysis, researchers assessed the effects of lenvatinib compared with sorafenib on health-related quality of life in patients with hepatocellular carcinoma.
Sequential Combination of Markers May Help Reduce Need for Liver Biopsies in NAFLD
Investigators conducted an individual patient data meta-analysis to assess the LSM-VCTE and compare it with the FIB-4 and NFS scores in order to develop diagnostic strategies that could reduce the need for liver biopsies.
Statin Use Linked to Reduced Incident Cancer Risk in Heart Failure
Statin use was linked to a lower risk for incident cancer and cancer-related mortality in heart failure.
Using Urinary NGAL as a Biomarker for AKI in Cirrhosis
A team of investigators conducted a prospective cohort study to validate NGAL as a diagnostic and prognostic tool for AKI in cirrhosis within North America.
COVID-19 mRNA Vaccine Reduces Infections in Cirrhosis Patients
Although the immune response is slow and the level of protection against infection is modest, mRNA vaccine reduces COVID-19-related hospitalizations and deaths in patients with cirrhosis.
Sofosbuvir With Velpatasvir for HCV Effective, Well Tolerated Regardless of Cirrhosis Status
Researchers used real-world data to determine the impact of hepatic fibrosis on the effectiveness of sofosbuvir/velpatasvir treatment in an Asian population with hepatitis C virus infection.
Adipose Tissue and the Pathogenesis of Insulin Resistance in Patients with Obesity and NAFLD
Researchers investigated the underlying mechanisms responsible for insulin resistance in patients with obesity and NAFLD.
Severe NAFLD Associated With High Subclinical Atherosclerosis Risk
The goal of this study was to determine the relationship between subclinical coronary artery disease and the severity of nonalcoholic fatty liver disease.
Access to Liver Transplantation Scarce Among Veterans With Cirrhosis
Researchers evaluated the rates of and factors associated with referral, wait-listing, and receipt of liver allografts.
Hepatitis B Virus Monitoring Needed After Liver Transplantation
Health care providers should test liver recipients for hepatitis B virus (HBV) given the slight risk for unexpected donor-derived HBV infection.
Predictors of Nonalcoholic Steatohepatitis in Patients With Type 1 Diabetes
Investigators sought to determine if a relationship exists between nonalcoholic fatty liver and adipose tissue, waist-to-height ratio, and body mass index in patients with type 1 diabetes.
Patients With Nonalcoholic Steatohepatitis and Renal Failure at Increased Risk for Mortality, Hospital Utilization
Investigators evaluated rates of mortality, hospital utilization, and hospital charges among patients with NASH with and without concurrent kidney failure.
Hepatitis B Surface Antigen Seroclearance in HBV Unlikely With Entecavir, Tenofovir
Investigators assessed factors affecting HBsAg seroclearance in individuals with hepatitis B virus infection.
Universal Screening for Hepatitis B Virus Offers Better Health Outcomes, Cost Savings
Researchers assessed the cost-effectiveness of universal adult screening for chronic hepatitis B virus infection.
Hepatitis C Treatment-As-Prevention Reduces Virus Incidence In a Prison Setting
Investigators assessed the effectiveness of hepatitis C virus treatment-as-prevention in a prison setting.
Apatinib Improves Overall Survival in Pretreated Advanced Hepatocellular Carcinoma
Investigators assessed the safety and efficacy of apatinib in pretreated hepatocellular carcinoma and its effects on overall survival.
Tri-Antigenic vs Mono-Antigenic Vaccine for Hepatitis B Virus Prevention
A team of researchers sought to compare the seroprotection rate of a hepatitis B virus tri-antigenic vaccine with that of a mono-antigenic vaccine in adults.
Statistical Model With a-Fetoprotein Response Better Predicts Success of Liver Transplant in Patients With Hepatocellular Carcinoma Recurrence
Researchers aimed to validate use of the NCYA score and its incorporation of AFP-R in the selection of patients for liver transplant due to HCC recurrence.
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