Baraclude was not significantly associated with an increased risk of malignant neoplasms compared to other standard-of-care HBV nucleos(t)ides.
Liver injury episodes due to kratom (Mitragyna speciosa) are increasing in the United States, and chemical analysis can confirm the presence of this botanical in herbal and dietary supplements linked to cases of severe liver injury.
For older patients with type 2 diabetes mellitus, higher levels of seroprotection against the hepatitis B virus were obtained following the receipt of the 2-dose vaccine vs the 3-dose vaccine.
Researchers suggest that the hepatitis E virus remains a worldwide threat because more needs to be investigated about its transmission.
Investigators found that young age, high HCV viral load, and HCV/HIV co-infection were the factors associated with an increased transmission risk.
As a part of the LIVERHOPE project, researchers evaluated the safety of 2 different simvastatin doses in combination with rifaximin vs placebo in patients with decompensated cirrhosis.
Researchers found data that showed entecavir is safe in the treatment of hepatitis B virus in patients who are undergoing hemodialysis.
Investigators aimed to evaluate the safety and tolerability of ubrogepant, focusing on hepatic safety, when administered intermittently with high-frequency dosing in healthy participants.
Researchers found data that showed early initiation of antiviral therapy with lamivudine in infants with hepatitis B caused a rapid loss of HBsAg.
Researchers found data that showed in patients with hepatitis C, the presence of resistance-associated substitutions did not change the sustained viral response after treatment failure with other direct-acting-antivirals with the combination of sofosbuvir, velpatasvir, and voxilaprevir.
Researchers found data that showed in pregnant women with hepatitis B, the antiviral medications telbivudine and tenofovir disoproxil fumarate were safe, effective, and well tolerated, while reducing transmission of hepatitis B from mother to child during the perinatal period.
Researchers explore factors that surround creating a vaccine to combat hepatitis C virus infection.
Researchers found data that showed chronic hepatitis C virus infection and associated carotid intima-media thickness and plaque are predictors for cerebrovascular disease.
Obesity was found to be associated with elevated markers of liver damage in children and adolescents.
The FDA has granted Fast Track designation to TERN-101 (Terns Pharmaceuticals) for the treatment of non-alcoholic steatohepatitis.
Hepatic-directed vesicle insulin, a novel liver-targeted rapid-acting insulin formulation for type 1 diabetes, is noninferior to insulin lispro for improvement of HbA1c and is associated with a lower hypoglycemia risk in some patients.
Acne patients receiving isotretinoin may not need continued testing when experiencing low-grade liver enzyme abnormalities, as most mild elevations do not worsen.
Two studies on hepatitis A and hepatitis B vaccination highlight opportunities to improve coverage of ≥2 doses of hepatitis A vaccine in children and hepatitis B vaccine series completion in adults.
Hepatitis E seropositivity is higher in older adults and may represent an increased exposure risk over time; in contrast, the opioid crisis has caused a demographic shift in hepatitis C infection, which is now a predominately millennial disease.
Direct-acting antiviral agents for treatment of hepatitis C virus may have higher sustained virologic responses in people coinfected with hepatitis B and hepatitis C viruses.