Prevalence of Primary Sclerosing Cholangitis in IBD Explored
The pooled prevalence of primary sclerosing cholangitis (PSC) is 2.16 percent in patients with inflammatory bowel disease.
Cholestatic Liver Disease
CHOLESTATIC LIVER DISEASE
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Prevalence of Primary Sclerosing Cholangitis in Patients With IBD
Investigators assessed how certain factors influence the prevalence of primary sclerosing cholangitis in patients with inflammatory bowel disease.
Prevalence of Primary Sclerosing Cholangitis in IBD Examined
The global prevalence of primary sclerosing cholangitis ranges from 0.96 percent in Crohn disease to 2.47 percent in ulcerative colitis.
Hypothermic Machine Perfusion in DCD Liver Transplantation
Investigators compared the incidence of nonanastomotic biliary strictures in patients receiving a liver obtained after circulatory death that had undergone hypothermic oxygenated machine perfusion or conventional static cold storage.
Bezafibrate Constitutes New Treatment Option for Cholestasis-Associated Pruritus
The FITCH trial was conducted to evaluate the effect of bezafibrate on pruritus in patients with fibrosing cholangiopathies (PSC, PBC, and SSC).
PSC With UC Presents as a Unique Disease Phenotype
Researchers studied the histologic and clinical features of primary sclerosing cholangitis patients with and without IBD to predict disease severity.
Clinical Characteristics in IgG4-SC With vs Without AIP
Researchers aimed to compare clinical characteristics of patients with IgG4-SC and AIP vs without.
Further Research Needed for Patients With Primary Sclerosing Cholangitis
There are concerns between the association between exposure to various drugs and outcomes in patients with primary sclerosing cholangitis IBD.
Common Therapy for Obstetric Cholestasis Found Ineffective
For women with intrahepatic cholestasis of pregnancy, treatment with ursodeoxycholic acid does not reduce adverse perinatal outcomes, according to a study published online Aug. 1 in The Lancet.
Radiologists Performing More Paracenteses
The researchers found that from 2004 to 2016, there was an increase in the proportion of all paracentesis and thoracentesis procedures performed by radiologists (70 to 80 percent and 47 to 66 percent, respectively).
Evaluating Long-Term Outcomes of Pediatric-Onset Primary Sclerosing Cholangitis
Researchers conducted a retrospective cohort study to determine the clinical features of pediatric patients with PSC in a Japanese cohort to evaluate long-term outcomes. They discovered that primary sclerosing cholangitis (PSC)-autoimmune hepatitis overlap is the primary phenotype linked to poor long-term outcomes.
GLOBE, UK-PBC Models Predict Cirrhosis-Related Complications in PBC
Two risk stratification models, GLOBE and UK-PBC, performed well in predicting future complications related to cirrhosis in patients with primary biliary cholangitis.
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