Cholestatic Liver Disease

Latest Articles

Prevalence of Primary Sclerosing Cholangitis in IBD Examined

The global prevalence of primary sclerosing cholangitis ranges from 0.96 percent in Crohn disease to 2.47 percent in ulcerative colitis.

Hypothermic Machine Perfusion in DCD Liver Transplantation

By

Colby Stong

Investigators compared the incidence of nonanastomotic biliary strictures in patients receiving a liver obtained after circulatory death that had undergone hypothermic oxygenated machine perfusion or conventional static cold storage.

Clinical Characteristics in IgG4-SC With vs Without AIP

By

Brandon May

Researchers aimed to compare clinical characteristics of patients with IgG4-SC and AIP vs without.

Bezafibrate Constitutes New Treatment Option for Cholestasis-Associated Pruritus

By

Virginia A. Schad, PharmD, RPh

The FITCH trial was conducted to evaluate the effect of bezafibrate on pruritus in patients with fibrosing cholangiopathies (PSC, PBC, and SSC).

PSC With UC Presents as a Unique Disease Phenotype

By

Jessica Nye, PhD

Researchers studied the histologic and clinical features of primary sclerosing cholangitis patients with and without IBD to predict disease severity.

Further Research Needed for Patients With Primary Sclerosing Cholangitis

By

Gastroenterology Advisor Contributing Writer

There are concerns between the association between exposure to various drugs and outcomes in patients with primary sclerosing cholangitis IBD.

Common Therapy for Obstetric Cholestasis Found Ineffective

For women with intrahepatic cholestasis of pregnancy, treatment with ursodeoxycholic acid does not reduce adverse perinatal outcomes, according to a study published online Aug. 1 in The Lancet.

Radiologists Performing More Paracenteses

The researchers found that from 2004 to 2016, there was an increase in the proportion of all paracentesis and thoracentesis procedures performed by radiologists (70 to 80 percent and 47 to 66 percent, respectively).

Evaluating Long-Term Outcomes of Pediatric-Onset Primary Sclerosing Cholangitis

By

Gastroenterology Advisor Contributing Writer

Researchers conducted a retrospective cohort study to determine the clinical features of pediatric patients with PSC in a Japanese cohort to evaluate long-term outcomes. They discovered that primary sclerosing cholangitis (PSC)-autoimmune hepatitis overlap is the primary phenotype linked to poor long-term outcomes.

GLOBE, UK-PBC Models Predict Cirrhosis-Related Complications in PBC

By

Gastroenterology Advisor Contributing Writer

Two risk stratification models, GLOBE and UK-PBC, performed well in predicting future complications related to cirrhosis in patients with primary biliary cholangitis.