Investigators analyzed the effects of TAK-101 from the induction of gliadin-specific T-cell tolerance in patients with biopsy-confirmed celiac disease.
The systemic effects of the gut microbiome persist throughout the life course, though neonatal and early-life disruptions may have the greatest consequences on gut health.
Celiac disease is known to be associated with depression and anxiety in adults with type 1 diabetes and celiac disease. In this study, researchers examine the theory in adolescents with T1D and celiac disease.
Despite numerous studies showing a potential association between celiac disease and small bowel cancer, there is a lack of data evaluating the risk of specific subtypes of small bowel cancer.
Investigators assessed the predictive capacity and diagnostic yield of a minimum 10-fold increase in serum IgA antitissue transglutaminase antibody levels in celiac disease.
Investigators characterized the gut microbiota of children with celiac disease to collect data on the determinants of the microbiota likely to change in children following a gluten-free diet.
To improve the assessment and management of patients with seronegative enteropathies, the AGA reviewed studies that reported on the management of patients with suspected celiac disease or other enteropathies not related to gluten who had received negative results from serologic tests.
Pediatric patients with newly diagnosed celiac disease (CD) reported lower health-related quality of life (HRQOL) when compared with healthy children with nonceliac gastrointestinal (GI) complaints, according to a study published in the Journal of Pediatric Gastroenterology & Nutrition. CD is a common chronic condition associated with broad range of physical and psychosocial problems. In this…
High gluten intake during the first 5 years of life was a statistically significant, independent risk factor for both celiac disease (CD) autoimmunity and CD in genetically predisposed children.
Researchers found approximately one-third of patients with type 1 diabetes and celiac disease were able to achieve sustained celiac-specific antibody negativity after celiac disease diagnosis.
Clinicians are encouraged to gain an understanding about when HLA genetic testing should be ordered, the type of test that should be ordered, and how to interpret results.
The researchers found that 360 of 477 FDRs identified were screened (mean screening rate per family, 79 ± 25 percent) and 160 FDRs (44 percent) were diagnosed with celiac disease.
Based on technical review and expert consensus, a guideline committee put together by the American Gastroenterological Association (AGA) released official recommendations on the laboratory evaluation of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D) in immunocompetent adults. This report was published in Gastroenterology. Members of the AGA guideline committee and authors of the technical review…