TAK-101 May Prevent Gluten-Induced Immune Activation in Celiac Disease
Investigators analyzed the effects of TAK-101 from the induction of gliadin-specific T-cell tolerance in patients with biopsy-confirmed celiac disease.
Celiac Disease
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Exploring the Impact of Nutrition on the Gut Microbiome
The systemic effects of the gut microbiome persist throughout the life course, though neonatal and early-life disruptions may have the greatest consequences on gut health.
Type 1 Diabetes With Celiac Disease Increases Depression Risk in Adolescents
Celiac disease is known to be associated with depression and anxiety in adults with type 1 diabetes and celiac disease. In this study, researchers examine the theory in adolescents with T1D and celiac disease.
Iron-Deficiency Anemia Secondary to Asymptomatic Celiac Disease: A Case Study
A 21-year-old woman presents with a complaint of continued iron deficiency despite treatment with oral iron supplementation.
Celiac Disease and Small Bowel Cancers: A Question of Risk
Despite numerous studies showing a potential association between celiac disease and small bowel cancer, there is a lack of data evaluating the risk of specific subtypes of small bowel cancer.
New Data Support No-Biopsy Approach for Celiac Disease Diagnosis
Investigators assessed the predictive capacity and diagnostic yield of a minimum 10-fold increase in serum IgA antitissue transglutaminase antibody levels in celiac disease.
Gluten-Free Diet Induces Changes in Intestinal Microbiota of Children With Celiac Disease
Investigators characterized the gut microbiota of children with celiac disease to collect data on the determinants of the microbiota likely to change in children following a gluten-free diet.
Caregivers of Children With Food Allergy Report Heightened Food Safety Concerns During COVID-19 Pandemic
The effect of coronavirus disease 2019 (COVID-19) on patients with food allergy and their parents and caregivers is substantial.
Celiac Disease Correlates With Increased Risk for Pancreatitis
Investigators of the retrospective study evaluated whether celiac disease is associated with an increased risk for pancreatitis.
IL-2 Levels Found to Be Earliest and Most Sensitive Biomarker of Acute Gluten Exposure
Investigators studied several biomarkers of celiac disease activity induced by gluten challenge.
Updated AGA Practice Guideline on Evaluating and Managing Seronegative Enteropathies
To improve the assessment and management of patients with seronegative enteropathies, the AGA reviewed studies that reported on the management of patients with suspected celiac disease or other enteropathies not related to gluten who had received negative results from serologic tests.
Early Introduction of Gluten Linked to Decline in Celiac Disease
Introduction of gluten from age 4 months is associated with a reduced prevalence of celiac disease.
Celiac Disease: Is There a Link With Environmental Chemicals and Metals?
A team of researchers recently evaluated serum concentrations of persistent organic pollutants to determine how they may affect celiac disease.
Effects of a Gluten-Free Diet in Patients With Type 1 Diabetes and Asymptomatic Celiac Disease
In individuals with type 1 diabetes who test positive for asymptomatic celiac disease, a gluten-free diet may increase postprandial glycemic levels.
Pediatric Patients With Newly Diagnosed Celiac Disease Report Lower HRQOL
Pediatric patients with newly diagnosed celiac disease (CD) reported lower health-related quality of life (HRQOL) when compared with healthy children with nonceliac gastrointestinal (GI) complaints, according to a study published in the Journal of Pediatric Gastroenterology & Nutrition. CD is a common chronic condition associated with broad range of physical and psychosocial problems. In this…
High Tissue-Transglutaminase Antibody Titer Can Lead to Celiac Disease
High tTGA titer, female sex, hypothyroidism, and history of autoimmune disease are significant predictors for a diagnosis of celiac disease in adults.
Does High Gluten Intake During Childhood Increase Risk for Celiac Disease?
High gluten intake during the first 5 years of life was a statistically significant, independent risk factor for both celiac disease (CD) autoimmunity and CD in genetically predisposed children.
Antibody Negativity, Growth, and Metabolic Control in T1D With Celiac Disease
Researchers found approximately one-third of patients with type 1 diabetes and celiac disease were able to achieve sustained celiac-specific antibody negativity after celiac disease diagnosis.
Guidelines When Performing HLA Testing for Celiac Disease
Clinicians are encouraged to gain an understanding about when HLA genetic testing should be ordered, the type of test that should be ordered, and how to interpret results.
Prevalence of Celiac Disease High in First-Degree Relatives
The researchers found that 360 of 477 FDRs identified were screened (mean screening rate per family, 79 ± 25 percent) and 160 FDRs (44 percent) were diagnosed with celiac disease.
AGA Recommendations for Evaluation of Functional Diarrhea and Diarrhea-Predominant IBS in Adults
Based on technical review and expert consensus, a guideline committee put together by the American Gastroenterological Association (AGA) released official recommendations on the laboratory evaluation of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D) in immunocompetent adults. This report was published in Gastroenterology. Members of the AGA guideline committee and authors of the technical review…
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