Modified Early Warning Score Predicts Deterioration in COVID-19 Patients
Study authors assessed the specificity and positive predictive value of a customized, institutional, early warning score for predicting decompensation in COVID-19 patients.
All articles by Bradley van Paridon
Therapeutic Enoxaparin Found to Decrease Need for Mechanical Ventilation in Patients With Severe COVID-19
The effect of therapeutic anticoagulation with enoxaparin vs prophylactic anticoagulation with unfractionated heparin was assessed in severe COVID-19 patients.
Clindamycin, Second-Generation Fluoroquinolones Associated With ‘High Level’ of Resistance in Clostridioides difficile
Metronidazole, vancomycin, fidaxomicin, meropenem, and piperacillin/tazobactam are rarely resistant to Clostridioides (Clostridium) difficile infection, while second-generation fluoroquinolones and clindamycin show highest risk.
Liver Stiffness Post HCV Anti-Viral Therapy Associated With Several Adverse Outcomes
Measuring liver stiffness should be considered after anti-viral treatment because it predicts adverse outcomes even beyond routinely available clinical predictors.
Futility Concerns Halt C difficile Vaccine Trial
The efficacy, immunogenicity, and safety of a Clostridioides difficile toxoid vaccine candidate was assessed.
Antibiotic Prescription Durations for Common Infections Often Exceeded Guidelines
Researchers identified 2889 sampled antibiotic prescriptions, which translates to a national estimate of 31,548,464, to assess if prescriptions are exceeding guideline-recommended dosing for Streptococcal pharyngitis, sinusitis, AOM, CAP, SSTI, and acute cystitis.
Safety, Efficacy of 8-Week Glecaprevir/Pibrentasvir for Treatment-Naive HCV Examined
Eight weeks of treatment with glecaprevir/pibrentasvir is both efficacious and well tolerated in treatment-naive patients with HCV.
Asymptomatic C diff Associated With Pathogen Reservoir, Affecting Carriers, Patients, Employees in ICU
Genomically-confirmed assessments of the risk for CDI found that asymptomatic carriers serve as viral reservoirs in clinical settings.
GII.4 Genotype Most Common in Sporadic Pediatric Acute Gastroenteritis
Children with GII.4 type norovirus had more severe symptoms and required more medical care.
Efficacy of Bundled HIV, HCV Testing for People With Substance Abuse Disorders Examined
By providing bundled HIV and HCV testing, substance use disorder treatment programs may create increased awareness of infection status among people with substance abuse disorders.
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