Allison Himmel, Author at Gastroenterology Advisor

Allison Himmel

All articles by Allison Himmel

Aspirin toxicity

Aspirin is a common over-the-counter medication valued for its anti-inflammatory, analgesic and antipyretic properties. However it can be highly toxic or even fatal with intentional or accidental overdose. Aspirin directly stimulates cerebral respiratory centers and inhibits the citric acid cycle, causing uncoupling of oxidative phosphorylation which ultimately leads to lactic acidosis. Patients who present with…

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