Using scoring systems, researchers investigated the prevalence and risk factors for fecal incontinence in patients with IBD.
Researchers analyzed anorectal pressures, anorectal and abdominal motion, and evacuation in healthy controls vs women with constipation.
Investigators assessed the efficacy of the addition of oxaliplatin to capecitabine-based postoperative chemoradiotherapy for treating locally advanced rectal cancer.
Investigators aimed to determine the optimal treatment order of chemoradiotherapy and chemotherapy for patients with locally advanced rectal cancer.
Investigators assessed disparities in the care and disease education needs of patients with Crohn’s perianal fistulas.
Investigators sought to evaluate the relationship between obesity and measures from high-resolution anorectal manometry and hindgut symptoms.
Researchers assessed the safety of laparoscopic surgery vs open surgery for rectal cancer using 10-year follow-up data.
The BLA submission is supported by data from the phase 2 POD1UM-202 study, which evaluated retifanlimab in patients with locally advanced or metastatic SCAC who progressed after platinum-based chemotherapy.
Researchers evaluated perianal involvement in patients with CD and compared disease course in those with severe vs non-severe perianal CD.
Researchers analyzed the relationship between adolescent simple sugar and sugar-sweetened beverages intake and the development of colorectal cancer.
While anal cancer is relatively uncommon in the general population, its incidence is substantially elevated in certain groups, including patients with HIV and certain autoimmune conditions.
The BLA is supported by data from the POD1UM-202 trial that evaluated retifanlimab in 94 adults with locally advanced or metastatic SCAC who progressed after platinum-based chemotherapy.
As Crohn disease perianal fistulas often do not respond to available treatments, researchers developed a patient-derived quality-of-life tool to evaluate the impact of the condition on patients.
The Company has begun shipping both the 8mcg and 24mcg capsules; the capsules are supplied in 60-count bottles.
Short-course radiotherapy followed by chemotherapy and total mesorectal excision improved outcomes for patients with high-risk locally advanced rectal cancer.
High level of organ preservation, improved QoL seen with short-course radiotherapy followed by transanal endoscopic microsurgery
If the current COVID-19 trends persist, the NCI estimates that the pandemic’s impact could threaten the trend of annually decreasing cancer mortality seen in the US since 1990.
Sometimes the distinctions between cancer treatment groups are a little blurry. Here’s a guide to their definitions and origins.
Digital manometry provides similar pressure readings compared with the gold-standard high-resolution anorectal manometry in patients with chronic constipation and fecal incontinence.
Survival and recurrence rates were not significantly different between patients with low rectal cancer who were treated with either local or total mesorectal excision.